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    nhr-34 Nuclear hormone receptor family member nhr-34 [ Caenorhabditis elegans ]

    Gene ID: 177800, updated on 9-Dec-2024

    Summary

    Official Symbol
    nhr-34
    Official Full Name
    Nuclear hormone receptor family member nhr-34
    Primary source
    WormBase:WBGene00003627
    Locus tag
    CELE_F58G6.5
    See related
    AllianceGenome:WB:WBGene00003627
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nhr-34 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    13
    Sequence:
    Chromosome: IV; NC_003282.8 (9664365..9675672, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Copper transport protein Neighboring gene Acetylcholine-gated chloride channel subunit acc-1;Ligand-gated ion channel 50 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Nuclear hormone receptor family member nhr-34
    NP_001023245.1
    • Confirmed by transcript evidence
    NP_001129859.1
    • Confirmed by transcript evidence
    NP_501716.2
    • Confirmed by transcript evidence
    NP_741480.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9664365..9675672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171412.5NP_741480.1  Nuclear hormone receptor family member nhr-34 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741480.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21006
      Conserved Domains (2) summary
      cd06960
      Location:1994
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:248419
      HOLI; Ligand binding domain of hormone receptors
    2. NM_069315.7NP_501716.2  Nuclear hormone receptor family member nhr-34 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501716.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21006
      Conserved Domains (2) summary
      cd06960
      Location:133208
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:362533
      HOLI; Ligand binding domain of hormone receptors
    3. NM_001028074.5NP_001023245.1  Nuclear hormone receptor family member nhr-34 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023245.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3GWB8, Q21006, Q7JM21, Q95NU3, Q9GTH8
      Conserved Domains (2) summary
      cd06960
      Location:151226
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:380551
      HOLI; Ligand binding domain of hormone receptors
    4. NM_001136387.4NP_001129859.1  Nuclear hormone receptor family member nhr-34 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001129859.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21006
      Conserved Domains (2) summary
      cd06960
      Location:83158
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:312483
      HOLI; Ligand binding domain of hormone receptors