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    B0303.7 SH3 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176220, updated on 9-Dec-2024

    Summary

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    Official Symbol
    B0303.7
    Official Full Name
    SH3 domain-containing protein
    Primary source
    WormBase:WBGene00015128
    Locus tag
    CELE_B0303.7
    See related
    AllianceGenome:WB:WBGene00015128
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in actin filament organization and cell migration. Orthologous to human SH3D19 (SH3 domain containing 19). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See B0303.7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (8693622..8699521)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Nicotinamide N-methyltransferase Neighboring gene putative 3-ketoacyl-CoA thiolase Neighboring gene Uncharacterized protein Neighboring gene Skn-1 dependent zygotic transcript 1 protein Neighboring gene Vacuolar protein sorting-associated protein 33A Neighboring gene Solute carrier family 12 protein B0303.11 Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SH3 domain-containing protein
    NP_001122671.1
    • Confirmed by transcript evidence
    NP_498918.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8693622..8699521
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066517.8 → NP_498918.3  SH3 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498918.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34258
      Conserved Domains (2) summary
      smart00326
      Location:194 → 247
      SH3; Src homology 3 domains
      cl17036
      Location:275 → 326
      SH3; Src Homology 3 domain superfamily

    2. NM_001129199.4 → NP_001122671.1  SH3 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122671.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9Z1J8
      Conserved Domains (2) summary
      smart00326
      Location:168 → 221
      SH3; Src homology 3 domains
      cl17036
      Location:249 → 300
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34258.5

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