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    Ice2 Interacts with the C terminus of ELL 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42507, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ice2provided by FlyBase
    Official Full Name
    Interacts with the C terminus of ELL 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0038860
    Locus tag
    Dmel_CG10825
    See related
    AllianceGenome:FB:FBgn0038860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10825; Dmel\CG10825
    Summary
    Part of super elongation complex. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ice2 in Genome Data Viewer
    Location:
    93C1-93C1; 3-71 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21130216..21132720)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16955938..16958442)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene supernumerary limbs Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 93a Neighboring gene tRNA methyltransferase 7-34 Neighboring gene Ubiquitin specific protease 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Epigenetic Regulation of ALS and CMT: A Lesson from Drosophila Models. Yamaguchi M, et al. Int J Mol Sci, 2021 Jan 6. PMID 33419039, Free PMC Article
    2. The little elongation complex regulates small nuclear RNA transcription. Smith ER, et al. Mol Cell, 2011 Dec 23. PMID 22195968, Free PMC Article
    3. A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. Lunardi A, et al. Proc Natl Acad Sci U S A, 2010 Apr 6. PMID 20308539, Free PMC Article
    4. Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. Manta AK, et al. Fly (Austin), 2017 Apr 3. PMID 27960592, Free PMC Article
    5. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of super elongation complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of transcription elongation factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription elongation factor complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_001097852.1
    • interacts with the C terminus of ELL 2, isoform C
    NP_650946.3
    • interacts with the C terminus of ELL 2, isoform A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21130216..21132720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142689.4 → NP_650946.3  uncharacterized protein Dmel_CG10825 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650946.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SZZ8, Q9VDE0
      Related
      FBpp0083418
      Conserved Domains (1) summary
      pfam10505
      Location:396 → 610
      NARG2_C; NMDA receptor-regulated gene protein 2 C-terminus

    2. NM_001104382.2 → NP_001097852.1  uncharacterized protein Dmel_CG10825 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097852.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGQ6
      Conserved Domains (1) summary
      pfam10505
      Location:106 → 320
      NARG2_C; NMDA receptor-regulated gene protein 2 C-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IGQ6 Q8IGQ6
    Q8SZZ8.1 Q8SZZ8

    Gene LinkOut

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