U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Mau2 Mau2 sister chromatid cohesion factor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41830, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Mau2provided by FlyBase
    Official Full Name
    Mau2 sister chromatid cohesion factorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038300
    Locus tag
    Dmel_CG4203
    See related
    AllianceGenome:FB:FBgn0038300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4203; Dmel\CG4203; FBgn0038300; mau-2; Mau-2; MAU-2; MAU2
    Summary
    Predicted to enable double-stranded DNA binding activity. Predicted to be involved in axon guidance and maintenance of mitotic sister chromatid cohesion. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of SMC loading complex. Orthologous to human MAU2 (MAU2 sister chromatid cohesion factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Mau2 in Genome Data Viewer
    Location:
    88E3-88E3; 3-56 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15209204..15211347)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11034926..11037069)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Serpin 88Ea Neighboring gene Serpin 88Eb Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Shal Interactor of Di-Leucine Motif Neighboring gene uncharacterized protein Neighboring gene mir-9383 stem loop

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. mau-2 acts cell-autonomously to guide axonal migrations in Caenorhabditis elegans. Bénard CY, et al. Development, 2004 Dec. PMID 15539489
    2. Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene. Rollins RA, et al. Mol Cell Biol, 2004 Apr. PMID 15060134, Free PMC Article
    3. Cohesin, gene expression and development: lessons from Drosophila. Dorsett D. Chromosome Res, 2009. PMID 19308700, Free PMC Article
    4. The Drosophila melanogaster model for Cornelia de Lange syndrome: Implications for etiology and therapeutics. Dorsett D. Am J Med Genet C Semin Med Genet, 2016 Jun. PMID 27097273, Free PMC Article
    5. Full circle: a brief history of cohesin and the regulation of gene expression. Horsfield JA. FEBS J, 2023 Apr. PMID 35048511

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in maintenance of mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maintenance of mitotic sister chromatid cohesion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SMC loading complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SMC loading complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Mau2 sister chromatid cohesion factor
    Names
    CG4203-PA
    Mau2-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15209204..15211347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142171.4 → NP_650428.1  Mau2 sister chromatid cohesion factor [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650428.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VFC0
      Related
      FBpp0082507
      Conserved Domains (1) summary
      pfam10345
      Location:14 → 563
      Cohesin_load; Cohesin loading factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFC0.1 Q9VFC0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous