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    CG7675 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42211, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7675provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038610
    Locus tag
    Dmel_CG7675
    See related
    AllianceGenome:FB:FBgn0038610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7675
    Summary
    Predicted to enable all-trans-retinol dehydrogenase (NADP+) activity. Located in cytosol. Is expressed in several structures, including adult brain cell body rind; adult head; adult heart; gut section; and synaptic neuropil domain. Orthologous to human RDH14 (retinol dehydrogenase 14). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7675 in Genome Data Viewer
    Location:
    91A4-91A4; 3-63 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18378124..18381178, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14203846..14206900, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR14310 Neighboring gene long non-coding RNA:CR44946 Neighboring gene uncharacterized protein Neighboring gene corona Neighboring gene Vacuolar H[+] ATPase 100kD subunit 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease. Xun Z, et al. Mol Cell Proteomics, 2008 Jul. PMID 18353766, Free PMC Article
    2. A genome-wide association study for nutritional indices in Drosophila. Unckless RL, et al. G3 (Bethesda), 2015 Jan 12. PMID 25583649, Free PMC Article
    3. Functional characterization and gene expression profiling of Drosophila melanogaster short dADA2b isoform-containing dSAGA complexes. Pankotai T, et al. BMC Genomics, 2013 Jan 22. PMID 23336284, Free PMC Article
    4. The transcriptional response of Drosophila melanogaster to infection with the sigma virus (Rhabdoviridae). Carpenter J, et al. PLoS One, 2009 Aug 31. PMID 19718442, Free PMC Article
    5. Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat. Napoletano F, et al. EMBO J, 2011 Mar 2. PMID 21278706, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables all-trans-retinol dehydrogenase (NADP+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7675-PA
    CG7675-PB
    CG7675-PC
    CG7675-PD
    CG7675-PE
    NP_001287390.1
    NP_001287391.1
    NP_650717.1
    NP_732334.1
    NP_996233.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18378124..18381178 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206511.2 → NP_996233.1  uncharacterized protein Dmel_CG7675, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0J5
      Conserved Domains (2) summary
      cd05327
      Location:3 → 271
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
      PRK06196
      Location:3 → 278
      PRK06196; oxidoreductase; Provisional

    2. NM_001300461.1 → NP_001287390.1  uncharacterized protein Dmel_CG7675, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287390.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQ98, Q9VE80, Q9VE81
      Conserved Domains (2) summary
      cd05327
      Location:52 → 320
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
      PRK06196
      Location:52 → 327
      PRK06196; oxidoreductase; Provisional

    3. NM_169809.3 → NP_732334.1  uncharacterized protein Dmel_CG7675, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732334.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0J5
      Related
      FBpp0083002
      Conserved Domains (2) summary
      cd05327
      Location:3 → 271
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
      PRK06196
      Location:3 → 278
      PRK06196; oxidoreductase; Provisional

    4. NM_142460.3 → NP_650717.1  uncharacterized protein Dmel_CG7675, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650717.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQ98, Q9VE80, Q9VE81
      Related
      FBpp0083003
      Conserved Domains (2) summary
      cd05327
      Location:52 → 320
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
      PRK06196
      Location:52 → 327
      PRK06196; oxidoreductase; Provisional

    5. NM_001300462.1 → NP_001287391.1  uncharacterized protein Dmel_CG7675, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287391.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0J5
      Conserved Domains (2) summary
      cd05327
      Location:3 → 271
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
      PRK06196
      Location:3 → 278
      PRK06196; oxidoreductase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T0J5 Q8T0J5
    Q9VE80 Q9VE80

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