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    inaF-A inaF-A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740676, updated on 9-Dec-2024

    Summary

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    Official Symbol
    inaF-Aprovided by FlyBase
    Official Full Name
    inaF-Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085351
    Locus tag
    Dmel_CG34322
    See related
    AllianceGenome:FB:FBgn0085351
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG34322; Dmel\CG34322; Dm_X:58729; inaF; InaF; INAF; INAF-A
    Summary
    Predicted to enable channel regulator activity. Involved in response to light stimulus. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See inaF-A in Genome Data Viewer
    Location:
    10D8-10E1; 1-36 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11726390..11733895, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11620423..11627928, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pretaporter Neighboring gene Transport and Golgi organization 10 Neighboring gene uncharacterized protein Neighboring gene inaF-D Neighboring gene inaF-B Neighboring gene inaF-C Neighboring gene pseudo Neighboring gene miniature Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus. Cheng Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 6. PMID 17968007, Free PMC Article
    2. INAF, a protein required for transient receptor potential Ca(2+) channel function. Li C, et al. Proc Natl Acad Sci U S A, 1999 Nov 9. PMID 10557345, Free PMC Article
    3. Distinct TRP channels are required for warm and cool avoidance in Drosophila melanogaster. Rosenzweig M, et al. Proc Natl Acad Sci U S A, 2008 Sep 23. PMID 18787131, Free PMC Article
    4. Subcellular translocation of the eGFP-tagged TRPL channel in Drosophila photoreceptors requires activation of the phototransduction cascade. Meyer NE, et al. J Cell Sci, 2006 Jun 15. PMID 16735439, Free PMC Article
    5. Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity. Campbell JL, et al. J Neurogenet, 2009. PMID 19863272, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
      Title: A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables channel regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of membrane potential ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in response to light stimulus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inaF-A
    Names
    CG34322-PA
    inaF-A-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11726390..11733895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103490.2 → NP_001096960.1  inaF-A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096960.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUT0
      Conserved Domains (1) summary
      pfam15018
      Location:32 → 66
      InaF-motif; TRP-interacting helix
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JUT0 A8JUT0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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