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    CG12674 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33384, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG12674provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031388
    Locus tag
    Dmel_CG12674
    See related
    AllianceGenome:FB:FBgn0031388
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12674
    Summary
    Predicted to be involved in transcription elongation by RNA polymerase II. Predicted to be part of Cdc73/Paf1 complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12674 in Genome Data Viewer
    Location:
    22C2-22C2; 2-4 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2079919..2081286)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2079919..2081286)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Kinetochore and EB1 associated basic protein Neighboring gene Odorant receptor 22c Neighboring gene defective proboscis extension response 3 Neighboring gene long non-coding RNA:CR44808 Neighboring gene long non-coding RNA:CR44055

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A germline PAF1 paralog complex ensures cell type-specific gene expression. Vilstrup AP, et al. Genes Dev, 2024 Oct 16. PMID 39332828,
    2. A Drosophila screen identifies a role for histone methylation in ER stress preconditioning. Owings KG, et al. G3 (Bethesda), 2024 Feb 7. PMID 38098286, Free PMC Article
    3. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12674-PA
    CG12674-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2079919..2081286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134800.4 → NP_608644.1  uncharacterized protein Dmel_CG12674, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608644.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ73
      Related
      FBpp0077500
      Conserved Domains (1) summary
      pfam03985
      Location:19 → 213
      Paf1; Paf1

    2. NM_001272974.1 → NP_001259903.1  uncharacterized protein Dmel_CG12674, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259903.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PC82
      Conserved Domains (1) summary
      pfam03985
      Location:19 → 213
      Paf1; Paf1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PC82 M9PC82
    Q9VQ73 Q9VQ73

    Gene LinkOut

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