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    CG1440 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31776, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG1440provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030038
    Locus tag
    Dmel_CG1440
    See related
    AllianceGenome:FB:FBgn0030038
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1440
    Summary
    Predicted to enable aminopeptidase activity and cysteine-type peptidase activity. Predicted to be involved in homocysteine catabolic process and response to toxic substance. Located in cytosol. Is expressed in several structures, including Malpighian tubule primordium; adult brain; epithelium; gut section; and head epidermis primordium. Orthologous to human BLMH (bleomycin hydrolase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG1440 in Genome Data Viewer
    Location:
    7E9-7E9; 1-23 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8437057..8441264)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8331090..8335297)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene leg arista wing complex Neighboring gene TATA box binding protein-related factor 2 Neighboring gene uncharacterized protein Neighboring gene Mitoguardin Neighboring gene uncharacterized protein Neighboring gene optomotor-blind-related-gene-1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables aminopeptidase activity  
    enables cysteine-type aminopeptidase activity  
    enables cysteine-type peptidase activity  
    enables cysteine-type peptidase activity  
    Process Evidence Code Pubs
    involved_in homocysteine catabolic process  
    involved_in proteolysis  
    involved_in response to toxic substance  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytosol PubMed 

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG1440-PA
    CG1440-PB
    CG1440-PC
    CG1440-PD
    NP_001096906.1
    NP_001096907.1
    NP_001285018.1
    NP_572477.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      8437057..8441264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298089.1 → NP_001285018.1  uncharacterized protein Dmel_CG1440, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285018.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JEJ0
      Conserved Domains (1) summary
      pfam03051
      Location:102 → 547
      Peptidase_C1_2; Peptidase C1-like family
    2. NM_132249.2 → NP_572477.1  uncharacterized protein Dmel_CG1440, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572477.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3F6
      Related
      FBpp0071144
      Conserved Domains (1) summary
      pfam03051
      Location:39 → 484
      Peptidase_C1_2; Peptidase C1-like family
    3. NM_001103437.1 → NP_001096907.1  uncharacterized protein Dmel_CG1440, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096907.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV22
      Conserved Domains (1) summary
      pfam03051
      Location:62 → 507
      Peptidase_C1_2; Peptidase C1-like family
    4. NM_001103436.1 → NP_001096906.1  uncharacterized protein Dmel_CG1440, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096906.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV24
      Conserved Domains (1) summary
      cl23744
      Location:1 → 364
      Peptidase_C1; C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some ...
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