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    CG9536 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33904, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9536provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031818
    Locus tag
    Dmel_CG9536
    See related
    AllianceGenome:FB:FBgn0031818
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9536
    Summary
    Predicted to be involved in protein glycosylation and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in adult head and organism. Orthologous to human TMEM115 (transmembrane protein 115). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9536 in Genome Data Viewer
    Location:
    26D7-26D7; 2-20 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6474438..6476975, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6474438..6476975, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene HemK methyltransferase 1 Neighboring gene mummy Neighboring gene Sec61 alpha subunit Neighboring gene long non-coding RNA:CR45463 Neighboring gene Daxx-like protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sec61alpha is required for dorsal closure during Drosophila embryogenesis through its regulation of Dpp signaling. Wang X, et al. Dev Dyn, 2010 Mar. PMID 20112345, Free PMC Article
    2. Drosophila Trf4-1 involves in mRNA and primary miRNA transcription. Liu Y, et al. Biochem Biophys Res Commun, 2019 Apr 16. PMID 30837153
    3. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Raja SJ, et al. Mol Cell, 2010 Jun 25. PMID 20620954
    4. Analysis of the eye developmental pathway in Drosophila using DNA microarrays. Michaut L, et al. Proc Natl Acad Sci U S A, 2003 Apr 1. PMID 12655063, Free PMC Article
    5. A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway. Czech B, et al. Mol Cell, 2013 Jun 6. PMID 23665227, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein glycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9536-PA
    CG9536-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6474438..6476975 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201777.2 → NP_001188706.1  uncharacterized protein Dmel_CG9536, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188706.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMD2
      Conserved Domains (1) summary
      pfam08551
      Location:54 → 157
      DUF1751; Eukaryotic integral membrane protein (DUF1751)

    2. NM_135189.4 → NP_609033.1  uncharacterized protein Dmel_CG9536, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609033.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMD2
      Related
      FBpp0078897
      Conserved Domains (1) summary
      pfam08551
      Location:54 → 157
      DUF1751; Eukaryotic integral membrane protein (DUF1751)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMD2 Q9VMD2

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