U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FTSH8 FTSH protease 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837154, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FTSH8
    Official Full Name
    FTSH protease 8
    Primary source
    TAIR:AT1G06430
    Locus tag
    AT1G06430
    See related
    Araport:AT1G06430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    FTSH protease 8
    Summary
    encodes a FtsH protease that is localized to the chloroplast
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FTSH8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (1960031..1963189, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene trehalose-phosphatase/synthase 7 Neighboring gene DNA ligase-like protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. AtFtsH6 is involved in the degradation of the light-harvesting complex II during high-light acclimation and senescence. Zelisko A, et al. Proc Natl Acad Sci U S A, 2005 Sep 20. PMID 16157880, Free PMC Article
    2. Chloroplast and mitochondrial proteases in Arabidopsis. A proposed nomenclature. Adam Z, et al. Plant Physiol, 2001 Apr. PMID 11299370, Free PMC Article
    3. Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes. Sakamoto W, et al. Plant Cell, 2003 Dec. PMID 14630971, Free PMC Article
    4. In-depth analysis of the thylakoid membrane proteome of Arabidopsis thaliana chloroplasts: new proteins, new functions, and a plastid proteome database. Friso G, et al. Plant Cell, 2004 Feb. PMID 14729914, Free PMC Article
    5. New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy. Peltier JB, et al. J Biol Chem, 2004 Nov 19. PMID 15322131

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_100523.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within PSII associated light-harvesting complex II catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in chloroplast thylakoid membrane HDA PubMed 
    located_in extracellular region HDA PubMed 
    located_in thylakoid HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    FTSH protease 8
    NP_563766.3
    • FTSH protease 8 (FTSH8); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity, zinc ion binding; INVOLVED IN: PSII associated light-harvesting complex II catabolic process; LOCATED IN: thylakoid, chloroplast thylakoid membrane, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: FtsH extracellular protease family (TAIR:AT2G30950.1); Has 41562 Blast hits to 39150 proteins in 3282 species: Archae - 1592; Bacteria - 17123; Metazoa - 4966; Fungi - 3846; Plants - 3320; Viruses - 34; Other Eukaryotes - 10681 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1960031..1963189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331629.1 → NP_001321589.1  FTSH protease 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W585, Q94AL5, Q9SHI8
      UniProtKB/TrEMBL
      A0A178WM68, A0A5S9SXB2, A0A654E791
      Conserved Domains (1) summary
      CHL00176
      Location:77 → 669
      ftsH; cell division protein; Validated

    2. NM_001331628.1 → NP_001321590.1  FTSH protease 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W585, Q94AL5, Q9SHI8
      UniProtKB/TrEMBL
      A0A178WM68, A0A5S9SXB2, A0A654E791
      Conserved Domains (1) summary
      CHL00176
      Location:77 → 669
      ftsH; cell division protein; Validated

    3. NM_100523.6 → NP_563766.3  FTSH protease 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563766.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W585, Q94AL5, Q9SHI8
      UniProtKB/TrEMBL
      A0A178WM68, A0A5S9SXB2, A0A654E791
      Conserved Domains (1) summary
      CHL00176
      Location:77 → 669
      ftsH; cell division protein; Validated
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W585.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools