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    SERK1 somatic embryogenesis receptor-like kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843513, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SERK1
    Official Full Name
    somatic embryogenesis receptor-like kinase 1
    Primary source
    TAIR:AT1G71830
    Locus tag
    AT1G71830
    See related
    Araport:AT1G71830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSERK1; F14O23.21; F14O23_21; somatic embryogenesis receptor-like kinase 1; SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE 1
    Summary
    Plasma membrane LRR receptor-like serine threonine kinase expressed during embryogenesis in locules until stage 6 anthers, with higher expression in the tapetal cell layer. SERK1 and SERK2 receptor kinases function redundantly as an important control point for sporophytic development controlling male gametophyte production. later
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    Genomic context

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    See SERK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (27018158..27022117)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene cleavage stimulating factor 64 Neighboring gene Protein kinase superfamily protein Neighboring gene SEC6 Neighboring gene ncRNA Neighboring gene transducin family protein / WD-40 repeat family protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Subcellular localization and oligomerization of the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 protein. Shah K, et al. J Mol Biol, 2001 Jun 8. PMID 11397085
    2. AtSERK1 expression precedes and coincides with early somatic embryogenesis in Arabidopsis thaliana. Salaj J, et al. Plant Physiol Biochem, 2008 Jul. PMID 18515128
    3. The SERK1 receptor-like kinase regulates organ separation in Arabidopsis flowers. Lewis MW, et al. Plant J, 2010 Jun 1. PMID 20230490, Free PMC Article
    4. The SERK1 gene is expressed in procambium and immature vascular cells. Kwaaitaal MA, et al. J Exp Bot, 2007. PMID 17630293
    5. Role of threonines in the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 activation loop in phosphorylation. Shah K, et al. J Biol Chem, 2001 Nov 2. PMID 11509554

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hypermorphic SERK1 Mutations Function via a SOBIR1 Pathway to Activate Floral Abscission Signaling.
      Title: Hypermorphic SERK1 Mutations Function via a SOBIR1 Pathway to Activate Floral Abscission Signaling.
    2. In this study, we show that loss of function of SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE (SERK) genes results in aberrant embryo development. Fewer cortical, endodermal, and vascular cells are generated in the embryos of serk1 serk2 bak1 triple mutants.
      Title: SERK Receptor-like Kinases Control Division Patterns of Vascular Precursors and Ground Tissue Stem Cells during Embryo Development in Arabidopsis.
    3. The HAESA co-receptor SERK1, a positive regulator of the floral abscission pathway, allows for high-affinity sensing of the peptide hormone by binding to an Arg-His-Asn motif in IDA.
      Title: Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission.
    4. the existence of partial redundancy between SERK3 and SERK1 as well as the promoting or repressive activity of a single coreceptor in multiple simultaneously active pathways, is reported.
      Title: Transcriptional Analysis of serk1 and serk3 Coreceptor Mutants.
    5. these data provide genetic and biochemical evidence of the interaction and phosphorylation between SERK1/2 and EMS1 in anther development.
      Title: Two SERK Receptor-Like Kinases Interact with EMS1 to Control Anther Cell Fate Determination.
    6. SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin signaling.
      Title: On the Origin of SERKs: Bioinformatics Analysis of the Somatic Embryogenesis Receptor Kinases.
    7. Data indicate that the model included the contribution of the coreceptors SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 and SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE3 in BRASSINOSTEROID INSENSITIVE1 activities.
      Title: A mathematical model for the coreceptors SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 and SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE3 in BRASSINOSTEROID INSENSITIVE1-mediated signaling.
    8. serk1 bak1 bkk1 triple mutant exhibited drastically reduced expression of a number of genes critical to polar auxin transport, cell cycle, endodermis development and root meristem differentiatio
      Title: Somatic embryogenesis receptor kinases control root development mainly via brassinosteroid-independent actions in Arabidopsis thaliana.
    9. Mutations in SERK1 restore floral organ shedding, Golgi structure and trans-Golgi network in nev mutant flowers.
      Title: The SERK1 receptor-like kinase regulates organ separation in Arabidopsis flowers.
    10. essential for male microsporogenesis, independent from brassinolide
      Title: Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE proteins serve brassinosteroid-dependent and -independent signaling pathways.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105841.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables receptor serine/threonine kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane receptor protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within brassinosteroid mediated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within brassinosteroid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within floral organ abscission IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within microsporogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within microsporogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in plant ovule development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein autophosphorylation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    somatic embryogenesis receptor-like kinase 1
    NP_177328.1
    • somatic embryogenesis receptor-like kinase 1 (SERK1); FUNCTIONS IN: transmembrane receptor protein serine/threonine kinase activity, kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, protein complex; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: somatic embryogenesis receptor-like kinase 2 (TAIR:AT1G34210.1); Has 181670 Blast hits to 121787 proteins in 4268 species: Archae - 123; Bacteria - 18224; Metazoa - 45784; Fungi - 8994; Plants - 88758; Viruses - 411; Other Eukaryotes - 19376 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27018158..27022117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105841.4 → NP_177328.1  somatic embryogenesis receptor-like kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177328.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0LGI6, Q94AG2, Q9M9G3
      UniProtKB/TrEMBL
      A0A178W829, A0A178WDE0, A0A5S9WTH2, A0A654EGU8
      Conserved Domains (3) summary
      PLN00113
      Location:2 → 182
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      cd14664
      Location:308 → 579
      STK_BAK1_like; Catalytic domain of the Serine/Threonine Kinase, BRI1 associated kinase 1 and related STKs
      sd00033
      Location:73 → 94
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94AG2.2

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