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    SYP61 syntaxin of plants 61 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839749, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SYP61
    Official Full Name
    syntaxin of plants 61
    Primary source
    TAIR:AT1G28490
    Locus tag
    AT1G28490
    See related
    Araport:AT1G28490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSYP61; F3M18.7; F3M18_7; OSM1; syntaxin of plants 61
    Summary
    Encodes SYP61, one of 24 Arabidopsis syntaxins. Its mRNA has been shown to be expressed. SYP61 and SYP121 coordinate the trafficking of plasma membrane aquaporin PIP2;7 to modulate the cell membrane water permeability.
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    Genomic context

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    See SYP61 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (10015856..10018047)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Thioredoxin superfamily protein Neighboring gene hypothetical protein (DUF626) Neighboring gene Optic atrophy 3 protein (OPA3)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Hybrid Approach Enabling Large-Scale Glycomic Analysis of Post-Golgi Vesicles Reveals a Transport Route for Polysaccharides. Wilkop T, et al. Plant Cell, 2019 Mar. PMID 30760563, Free PMC Article
    2. Isolation and proteomic analysis of the SYP61 compartment reveal its role in exocytic trafficking in Arabidopsis. Drakakaki G, et al. Cell Res, 2012 Feb. PMID 21826108, Free PMC Article
    3. BFA-induced compartments from the Golgi apparatus and trans-Golgi network/early endosome are distinct in plant cells. Lam SK, et al. Plant J, 2009 Dec. PMID 19709389
    4. CESA TRAFFICKING INHIBITOR inhibits cellulose deposition and interferes with the trafficking of cellulose synthase complexes and their associated proteins KORRIGAN1 and POM2/CELLULOSE SYNTHASE INTERACTIVE PROTEIN1. Worden N, et al. Plant Physiol, 2015 Feb. PMID 25535279, Free PMC Article
    5. Arabidopsis SNAREs SYP61 and SYP121 coordinate the trafficking of plasma membrane aquaporin PIP2;7 to modulate the cell membrane water permeability. Hachez C, et al. Plant Cell, 2014 Jul. PMID 25082856, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The data provide evidence that SYP61 vesicles are involved in the transport and deposition of structural polysaccharides and glycoproteins.
      Title: A Hybrid Approach Enabling Large-Scale Glycomic Analysis of Post-Golgi Vesicles Reveals a Transport Route for Polysaccharides.
    2. Post-Golgi trafficking of PIP2;7 involves interactions with Qc-SNARE SYP61 and Qa-SNARE SYP121. The proper delivery of PIP2;7 to the plasma membrane depends on the activity of the two SNAREs, and that the SNAREs colocalize and physically interact.
      Title: Arabidopsis SNAREs SYP61 and SYP121 coordinate the trafficking of plasma membrane aquaporin PIP2;7 to modulate the cell membrane water permeability.
    3. SYP61 facilitates the trafficking of proteins to the plasma membrane.
      Title: Isolation and proteomic analysis of the SYP61 compartment reveal its role in exocytic trafficking in Arabidopsis.
    4. A functional characterization of AtVPS45 (for vacuolar protein sorting 45), a protein from the Sec1/Munc18 family in Arabidopsis (Arabidopsis thaliana) that interacts at the trans-Golgi network (TGN) with the SYP41/SYP61/VTI12 SNARE complex, is reported.
      Title: AtVPS45 is a positive regulator of the SYP41/SYP61/VTI12 SNARE complex involved in trafficking of vacuolar cargo.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036025.5
    NM_001332815.1
    NM_102617.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables SNAP receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SNAP receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in exocytosis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular protein transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in intracellular protein transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within_positive_effect plant-type cell wall cellulose biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in vesicle fusion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    syntaxin of plants 61
    NP_001031102.2
    • syntaxin of plants 61 (SYP61); CONTAINS InterPro DOMAIN/s: Target SNARE coiled-coil domain (InterPro:IPR000727), t-SNARE (InterPro:IPR010989), Syntaxin/epimorphin, conserved site (InterPro:IPR006012), Syntaxin 6, N-terminal (InterPro:IPR015260); BEST Arabidopsis thaliana protein match is: syntaxin of plants 52 (TAIR:AT1G79590.2); Has 786 Blast hits to 786 proteins in 195 species: Archae - 0; Bacteria - 4; Metazoa - 244; Fungi - 238; Plants - 166; Viruses - 0; Other Eukaryotes - 134 (source: NCBI BLink).
    NP_564310.1
    • syntaxin of plants 61 (SYP61); CONTAINS InterPro DOMAIN/s: Target SNARE coiled-coil domain (InterPro:IPR000727), Syntaxin/epimorphin, conserved site (InterPro:IPR006012), t-SNARE (InterPro:IPR010989), Syntaxin 6, N-terminal (InterPro:IPR015260); BEST Arabidopsis thaliana protein match is: syntaxin of plants 52 (TAIR:AT1G79590.2); Has 935 Blast hits to 902 proteins in 210 species: Archae - 0; Bacteria - 8; Metazoa - 293; Fungi - 255; Plants - 233; Viruses - 0; Other Eukaryotes - 146 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10015856..10018047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102617.4 → NP_564310.1  syntaxin of plants 61 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564310.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VYF3, Q946Y7, Q9SGP7
      UniProtKB/TrEMBL
      A0A178W5S5, A0A5S9WBA0, A0A654EEW4
      Conserved Domains (3) summary
      cd15841
      Location:156 → 212
      SNARE_Qc; SNARE motif, subgroup Qc
      pfam05739
      Location:189 → 240
      SNARE; SNARE domain
      cd21445
      Location:5 → 102
      SNARE_NTD_AtSYP61-like; N-terminal domain of Arabidopsis thaliana syntaxin-61 and similar proteins

    2. NM_001036025.5 → NP_001031102.2  syntaxin of plants 61 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031102.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HY64
      Conserved Domains (3) summary
      cd15841
      Location:117 → 173
      SNARE_Qc; SNARE motif, subgroup Qc
      pfam05739
      Location:150 → 201
      SNARE; SNARE domain
      pfam09177
      Location:18 → 60
      Syntaxin-6_N; Syntaxin 6, N-terminal

    3. NM_001332815.1 → NP_001321010.1  syntaxin of plants 61 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8APJ2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q946Y7.1

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