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    Pyridine nucleotide-disulfide oxidoreductase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843788, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Pyridine nucleotide-disulfide oxidoreductase family protein
    Primary source
    TAIR:AT1G74470
    Locus tag
    AT1G74470
    See related
    Araport:AT1G74470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1M20.15; F1M20_15; GERANYLGERANYL REDUCTASE
    Summary
    Encodes for a multifunctional protein with geranylgeranyl reductase activity shown to catalyze the reduction of prenylated geranylgeranyl-chlorophyll a to phytyl-chlorophyll a (chlorophyll a) and free geranylgeranyl pyrophosphate to phytyl pyrophosphate.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (27991165..27993445)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene RWP-RK domain-containing protein Neighboring gene Protein kinase superfamily protein Neighboring gene activation-tagged BRI1(brassinosteroid-insensitive 1)-suppressor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Metabolic compartmentation of plastid prenyllipid biosynthesis--evidence for the involvement of a multifunctional geranylgeranyl reductase. Keller Y, et al. Eur J Biochem, 1998 Jan 15. PMID 9492312
    2. Arabidopsis GERANYLGERANYL DIPHOSPHATE SYNTHASE 11 is a hub isozyme required for the production of most photosynthesis-related isoprenoids. Ruiz-Sola MÁ, et al. New Phytol, 2016 Jan. PMID 26224411
    3. LIL3, a light-harvesting-like protein, plays an essential role in chlorophyll and tocopherol biosynthesis. Tanaka R, et al. Proc Natl Acad Sci U S A, 2010 Sep 21. PMID 20823244, Free PMC Article
    4. Identification of proteins that interact with catalytically active calcium-dependent protein kinases from Arabidopsis. Uno Y, et al. Mol Genet Genomics, 2009 Apr. PMID 19130088
    5. New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy. Peltier JB, et al. J Biol Chem, 2004 Nov 19. PMID 15322131

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_106107.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables geranylgeranyl diphosphate reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables geranylgeranyl reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables geranylgeranyl reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chlorophyll biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chlorophyll biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vitamin E biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in chloroplast thylakoid membrane HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Pyridine nucleotide-disulfide oxidoreductase family protein
    NP_177587.1
    • Pyridine nucleotide-disulphide oxidoreductase family protein; FUNCTIONS IN: geranylgeranyl reductase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Geranylgeranyl reductase (InterPro:IPR010253), Geranylgeranyl reductase, plant/cyanobacteria (InterPro:IPR011774), Geranylgeranyl reductase, plant/prokaryotic (InterPro:IPR011777); Has 4540 Blast hits to 4539 proteins in 1185 species: Archae - 562; Bacteria - 2644; Metazoa - 5; Fungi - 25; Plants - 302; Viruses - 0; Other Eukaryotes - 1002 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27991165..27993445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106107.3 → NP_177587.1  Pyridine nucleotide-disulfide oxidoreductase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177587.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHM2, O49594, Q56YY5, Q8H170, Q9CA67
      UniProtKB/TrEMBL
      A0A178W817, A0A5S9WUC6
      Conserved Domains (1) summary
      PLN00093
      Location:17 → 467
      PLN00093; geranylgeranyl diphosphate reductase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CA67.1

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