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    PIP5K6 Phosphatidylinositol-4-phosphate 5-kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819987, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIP5K6
    Official Full Name
    Phosphatidylinositol-4-phosphate 5-kinase family protein
    Primary source
    TAIR:AT3G07960
    Locus tag
    AT3G07960
    See related
    Araport:AT3G07960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    phosphatidylinositol-4-phosphate 5-kinase 6
    Summary
    Encodes phosphatidylinositol-4-phosphate 5-kinase 6 (PIP5K6). Regulates clathrin-dependent endocytosis in pollen tubes.
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    Genomic context

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    See PIP5K6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (2534776..2538374)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Calcium-dependent ARF-type GTPase activating protein family Neighboring gene rhomboid protein-like protein Neighboring gene Pectin lyase-like superfamily protein Neighboring gene mitogen-activated protein kinase kinase kinase 6 Neighboring gene serine carboxypeptidase-like 27 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosphoinositides regulate clathrin-dependent endocytosis at the tip of pollen tubes in Arabidopsis and tobacco. Zhao Y, et al. Plant Cell, 2010 Dec. PMID 21189293, Free PMC Article
    2. Type B phosphatidylinositol-4-phosphate 5-kinases mediate Arabidopsis and Nicotiana tabacum pollen tube growth by regulating apical pectin secretion. Ischebeck T, et al. Plant Cell, 2008 Dec. PMID 19060112, Free PMC Article
    3. The Arabidopsis Phosphatidylinositol Phosphate 5-Kinase PIP5K3 is a key regulator of root hair tip growth. Kusano H, et al. Plant Cell, 2008 Feb. PMID 18281506, Free PMC Article
    4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pollen of T-DNA insertion lines deficient in both PIP5K4 and PIP5K5 exhibited reduced pollen germination and defects in pollen tube elongation.
      Title: Type B phosphatidylinositol-4-phosphate 5-kinases mediate Arabidopsis and Nicotiana tabacum pollen tube growth by regulating apical pectin secretion.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337755.1
    NM_111675.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within clathrin-dependent endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphatidylinositol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Phosphatidylinositol-4-phosphate 5-kinase family protein
    NP_187453.1
    • Phosphatidylinositol-4-phosphate 5-kinase family protein; FUNCTIONS IN: 1-phosphatidylinositol-4-phosphate 5-kinase activity, phosphatidylinositol phosphate kinase activity, ATP binding; INVOLVED IN: phosphatidylinositol metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup (InterPro:IPR016034), Phosphatidylinositol-4-phosphate 5-kinase, plant (InterPro:IPR017163), MORN motif (InterPro:IPR003409), Phosphatidylinositol-4-phosphate 5-kinase, core (InterPro:IPR002498); BEST Arabidopsis thaliana protein match is: phosphatidylinositol- 4-phosphate 5-kinase 5 (TAIR:AT2G41210.1); Has 28977 Blast hits to 7880 proteins in 615 species: Archae - 0; Bacteria - 4479; Metazoa - 4240; Fungi - 468; Plants - 2497; Viruses - 0; Other Eukaryotes - 17293 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2534776..2538374
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337753.1 → NP_001325990.1  Phosphatidylinositol-4-phosphate 5-kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMX2

    2. NM_001337754.1 → NP_001325991.1  Phosphatidylinositol-4-phosphate 5-kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMX3
      Conserved Domains (1) summary
      PLN03185
      Location:23 → 597
      PLN03185; phosphatidylinositol phosphate kinase; Provisional

    3. NM_111675.6 → NP_187453.1  Phosphatidylinositol-4-phosphate 5-kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187453.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SFB8
      UniProtKB/TrEMBL
      A0A178V9S0, A0A384KKN2, Q0WN55
      Conserved Domains (1) summary
      PLN03185
      Location:23 → 711
      PLN03185; phosphatidylinositol phosphate kinase; Provisional

    4. NM_001337755.1 → NP_001325989.1  Phosphatidylinositol-4-phosphate 5-kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMX2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SFB8.1

    Gene LinkOut

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