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    PDIL5-3 PDI-like 5-3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821603, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PDIL5-3
    Official Full Name
    PDI-like 5-3
    Primary source
    TAIR:AT3G20560
    Locus tag
    AT3G20560
    See related
    Araport:AT3G20560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 12; ATPDI12; ATPDIL5-3; PDI-like 5-3; PDI12; PROTEIN DISULFIDE ISOMERASE 12
    Summary
    Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Unlike several other PDI family members, transcript levels for this gene are not up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin).
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    Genomic context

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    See PDIL5-3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Sequence:
    Chromosome: 3; NC_003074.8 (7182013..7186567)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene early nodulin-like protein 9 Neighboring gene COBRA-like protein 10 precursor Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endoplasmic reticulum stress activates the expression of a sub-group of protein disulfide isomerase genes and AtbZIP60 modulates the response in Arabidopsis thaliana. Lu DP, et al. Mol Genet Genomics, 2008 Sep. PMID 18574595
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_112948.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein disulfide isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    PDI-like 5-3
    NP_566664.1
    • PDI-like 5-3 (PDIL5-3); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: cell redox homeostasis; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336), Protein of unknown function DUF1692 (InterPro:IPR012936); BEST Arabidopsis thaliana protein match is: Thioredoxin protein with domain of unknown function (DUF1692) (TAIR:AT1G50950.1); Has 5147 Blast hits to 3670 proteins in 375 species: Archae - 8; Bacteria - 112; Metazoa - 2494; Fungi - 904; Plants - 886; Viruses - 3; Other Eukaryotes - 740 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7182013..7186567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112948.3 → NP_566664.1  PDI-like 5-3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566664.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LJU2
      UniProtKB/TrEMBL
      A0A178VJQ3, A0A5S9XE22, A0A654FAC2
      Conserved Domains (3) summary
      cd02961
      Location:144 → 256
      PDI_a_family; Protein Disulfide Isomerase (PDIa) family, redox active TRX domains; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family include PDI ...
      pfam07970
      Location:293 → 464
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:7 → 98
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LJU2.1

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