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    LD Homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827904, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LD
    Official Full Name
    Homeodomain-like superfamily protein
    Primary source
    TAIR:AT4G02560
    Locus tag
    AT4G02560
    See related
    Araport:AT4G02560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    luminidependens; T10P11.15; T10P11_15
    Summary
    Encodes a nuclear localized protein with similarity to transcriptional regulators. Recessive mutants are late flowering. Expression of LFY is reduced in LD mutants.
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    14
    Sequence:
    Chromosome: 4; NC_003075.7 (1123475..1128490, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cullin 1 Neighboring gene NADH-ubiquinone oxidoreductase 24 kDa subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of an autonomous pathway complex that promotes flowering in Arabidopsis. Qi PL, et al. Nucleic Acids Res, 2022 Jul 22. PMID 35766439, Free PMC Article
    2. Luminidependens (LD) is an Arabidopsis protein with prion behavior. Chakrabortee S, et al. Proc Natl Acad Sci U S A, 2016 May 24. PMID 27114519, Free PMC Article
    3. The Arabidopsis flowering-time gene LUMINIDEPENDENS is expressed primarily in regions of cell proliferation and encodes a nuclear protein that regulates LEAFY expression. Aukerman MJ, et al. Plant J, 1999 Apr. PMID 10363371
    4. Isolation of LUMINIDEPENDENS: a gene involved in the control of flowering time in Arabidopsis. Lee I, et al. Plant Cell, 1994 Jan. PMID 7907507, Free PMC Article
    5. Flowering of Arabidopsis cop1 mutants in darkness. Nakagawa M, et al. Plant Cell Physiol, 2004 Apr. PMID 15111714

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Luminidependens (LD) is an Arabidopsis protein with prion behavior
      Title: Luminidependens (LD) is an Arabidopsis protein with prion behavior.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203731.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Homeodomain-like superfamily protein
    NP_001190660.1
    • luminidependens (LD); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Homeodomain-related (InterPro:IPR012287).
    NP_192165.1
    • luminidependens (LD); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Homeodomain-related (InterPro:IPR012287); Has 1085 Blast hits to 929 proteins in 132 species: Archae - 0; Bacteria - 17; Metazoa - 322; Fungi - 72; Plants - 440; Viruses - 0; Other Eukaryotes - 234 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1123475..1128490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116490.4 → NP_192165.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22771, Q0KG59, Q0KG64, Q0KG74, Q0KG76, Q0KG77, Q0KG78, Q0KG89, Q0KG90, Q0KG91, Q0KG92, Q0KG93, Q0KG94, Q0KG97, Q0WVK1, Q38796, Q58T20, Q9C5Z9
      UniProtKB/TrEMBL
      A0A5S9XR23, A0A654FL89
      Conserved Domains (2) summary
      smart00389
      Location:65 → 121
      HOX; Homeodomain
      cl00146
      Location:247 → 312
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme

    2. NM_001203731.2 → NP_001190660.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190660.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22771, Q0KG59, Q0KG64, Q0KG74, Q0KG76, Q0KG77, Q0KG78, Q0KG89, Q0KG90, Q0KG91, Q0KG92, Q0KG93, Q0KG94, Q0KG97, Q0WVK1, Q38796, Q58T20, Q9C5Z9
      UniProtKB/TrEMBL
      A0A5S9XR23, A0A654FL89
      Conserved Domains (2) summary
      smart00389
      Location:65 → 121
      HOX; Homeodomain
      cl00146
      Location:247 → 312
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38796.2

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