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    CPK18 calcium-dependent protein kinase 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829763, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPK18
    Official Full Name
    calcium-dependent protein kinase 18
    Primary source
    TAIR:AT4G36070
    Locus tag
    AT4G36070
    See related
    Araport:AT4G36070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    calcium-dependent protein kinase 18; T19K4.200; T19K4_200
    Summary
    member of Calcium Dependent Protein Kinase
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    Genomic context

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    See CPK18 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Sequence:
    Chromosome: 4; NC_003075.7 (17056587..17059706, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene endonuclease/exonuclease/phosphatase family protein Neighboring gene ncRNA Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene phosphotransferases/inositol or phosphatidylinositol kinase Neighboring gene oxidoreductase, 2OG-Fe(II) oxygenase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-Wide Identification and Characterization of Calcium Metabolism Related Gene Families in Arabidopsis thaliana and Their Regulation by Bacillus amyloliquefaciens Under High Calcium Stress. Gong J, et al. Front Plant Sci, 2021. PMID 34456948, Free PMC Article
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001204003.1
    NM_119774.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in response to calcium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    calcium-dependent protein kinase 18
    NP_001190932.1
    • calcium-dependent protein kinase 18 (CPK18); FUNCTIONS IN: protein serine/threonine kinase activity, calmodulin-dependent protein kinase activity, protein kinase activity, calcium ion binding, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: sperm cell, male gametophyte; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 16 (TAIR:AT2G17890.1).
    NP_195331.2
    • calcium-dependent protein kinase 18 (CPK18); FUNCTIONS IN: protein serine/threonine kinase activity, calmodulin-dependent protein kinase activity, protein kinase activity, ATP binding, calcium ion binding; INVOLVED IN: protein amino acid phosphorylation, N-terminal protein myristoylation; EXPRESSED IN: sperm cell, male gametophyte; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 16 (TAIR:AT2G17890.1); Has 123753 Blast hits to 121604 proteins in 3839 species: Archae - 181; Bacteria - 14516; Metazoa - 45843; Fungi - 14448; Plants - 26576; Viruses - 602; Other Eukaryotes - 21587 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17056587..17059706 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119774.3 → NP_195331.2  calcium-dependent protein kinase 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195331.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65644, Q1PE17
      UniProtKB/TrEMBL
      A0A5S9XZF5, A0A654FW12
      Conserved Domains (4) summary
      PTZ00184
      Location:367 → 514
      PTZ00184; calmodulin; Provisional
      smart00220
      Location:71 → 331
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00051
      Location:459 → 513
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd05117
      Location:70 → 330
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases

    2. NM_001204003.1 → NP_001190932.1  calcium-dependent protein kinase 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190932.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2V6, A0A5S9XZF5, A0A654FW12, F4JNY4
      Conserved Domains (4) summary
      PTZ00184
      Location:367 → 514
      PTZ00184; calmodulin; Provisional
      smart00220
      Location:71 → 331
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00051
      Location:459 → 513
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd05117
      Location:70 → 330
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1PE17.1

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