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    RING1A RING 1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834451, updated on 18-Sep-2024

    Summary

    Official Symbol
    RING1A
    Official Full Name
    RING 1A
    Primary source
    TAIR:AT5G44280
    Locus tag
    AT5G44280
    See related
    Araport:AT5G44280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA RING 1A; ATRING1A; K9L2.3; K9L2_3; RING 1A
    Summary
    Encodes a nuclear localized protein with similarity to animal polycomb repressive core complex1 (PRC1) core component RING.Appears to function redundantly with ATRING1b, a close paralog. Both interact physically with CLF and LHP1 and appear to function together to repress class I KNOX gene expression.
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    Genomic context

    See RING1A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (17835810..17839303, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene TPX2 (targeting protein for Xklp2) protein family Neighboring gene tRNA-Lys Neighboring gene ncRNA

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001161288.1
    NM_001344539.1
    NM_123795.5

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    part_of PRC1 complex PubMed 
    located_in cytoplasm  
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    RING 1A
    NP_001154760.1
    • RING 1A (RING1A); FUNCTIONS IN: zinc ion binding; INVOLVED IN: negative regulation of gene expression, epigenetic; LOCATED IN: nucleus, PRC1 complex; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; BEST Arabidopsis thaliana protein match is: RING 1B (TAIR:AT1G03770.1); Has 9014 Blast hits to 7495 proteins in 568 species: Archae - 41; Bacteria - 677; Metazoa - 3346; Fungi - 1171; Plants - 610; Viruses - 87; Other Eukaryotes - 3082 (source: NCBI BLink).
    NP_199241.2
    • RING 1A (RING1A); FUNCTIONS IN: zinc ion binding; INVOLVED IN: negative regulation of gene expression, epigenetic; LOCATED IN: nucleus, PRC1 complex; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING 1B (TAIR:AT1G03770.1); Has 87950 Blast hits to 40013 proteins in 1982 species: Archae - 331; Bacteria - 6780; Metazoa - 33639; Fungi - 11315; Plants - 4932; Viruses - 1435; Other Eukaryotes - 29518 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17835810..17839303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123795.5 → NP_199241.2  RING 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199241.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FKW0
      UniProtKB/TrEMBL
      A0A178UDU8, A0A654G8D7
      Conserved Domains (2) summary
      COG5222
      Location:134 → 216
      COG5222; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      cd16531
      Location:136 → 176
      RING-HC_RING1_like; RING finger, HC subclass, found in really interesting new gene proteins RING1, RING2 and similar proteins
    2. NM_001161288.1 → NP_001154760.1  RING 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154760.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G8D7, F4K8U4
    3. NM_001344539.1 → NP_001331587.1  RING 1A [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BEC3, A0A7G2FK32
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