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    PPX2 protein phosphatase X 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835619, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPX2
    Official Full Name
    protein phosphatase X 2
    Primary source
    TAIR:AT5G55260
    Locus tag
    AT5G55260
    See related
    Araport:AT5G55260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MCO15.21; MCO15_21; PPX-2; PROTEIN PHOSPHATASE X -2; protein phosphatase X 2
    Summary
    Encodes a protein with similarity to the catalytic subunit of the mammalian PPX protein phospatase.
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    Genomic context

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    See PPX2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (22416578..22418990)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene PEROXYGENASE 2 Neighboring gene IAA carboxylmethyltransferase 1 Neighboring gene hypothetical protein (DUF295) Neighboring gene homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis. Nageswaran DC, et al. Nat Plants, 2021 Apr. PMID 33846593, Free PMC Article
    2. Identification and molecular cloning of two homologues of protein phosphatase X from Arabidopsis thaliana. Pérez-Callejón E, et al. Plant Mol Biol, 1993 Dec. PMID 8292782
    3. PLATINUM SENSITIVE 2 LIKE impacts growth, root morphology, seed set, and stress responses. Kataya ARA, et al. PLoS One, 2017. PMID 28678890, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_124908.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within reciprocal meiotic recombination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase X 2
    NP_200337.1
    • protein phosphatase X 2 (PPX2); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: protein phosphatase X 1 (TAIR:AT4G26720.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22416578..22418990
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345121.1 → NP_001330655.1  protein phosphatase X 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBG2

    2. NM_124908.4 → NP_200337.1  protein phosphatase X 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200337.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22626, P48528, Q29Q40
      UniProtKB/TrEMBL
      A0A178UNE7, A0A5S9YE83
      Conserved Domains (1) summary
      cd07415
      Location:3 → 288
      MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48528.2

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