ABCG30 pleiotropic drug resistance 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ABCG30
Official Full Name: pleiotropic drug resistance 2
Primary source: TAIR:AT4G15230
Locus tag: AT4G15230
See related: Araport:AT4G15230
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATP-binding cassette G30; ATPDR2; DL3660W; FCAALL.241; PDR2; pleiotropic drug resistance 2
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Genomic context

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See ABCG30 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 24

Sequence:: Chromosome: 4; NC_003075.7 (8679754..8687519)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ABCG30 imports abscisic acid into the embryo, regulating seed germination.
Title: Abscisic acid transporters cooperate to control seed germination.
The Arabidopsis abcg30 (Atpdr2)mutant alters root exudation of Phytochemicals that significantly altered both the fungal and bacterial communities compared with the wild type. [ABCG30]
Title: An ABC transporter mutation alters root exudation of phytochemicals that provoke an overhaul of natural soil microbiota.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001341010.1

Supported by ESTs:

NM_001341012.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables ATPase-coupled transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables efflux transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in abscisic acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within carbohydrate export	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in import into cell	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intercellular transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of post-embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: pleiotropic drug resistance 2

NP_001319944.1

pleiotropic drug resistance 2 (PDR2); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, drug transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), Plant PDR ABC transporter associated (InterPro:IPR013581), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: pleiotropic drug resistance 13 (TAIR:AT4G15215.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

8679754..8687519

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001341011.1 → NP_001328800.1 pleiotropic drug resistance 2 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V3Y3, A0A1P8B5R0
NM_117611.5 → NP_193258.3 pleiotropic drug resistance 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193258.3

Status: REVIEWED

UniProtKB/Swiss-Prot

O23376, O23377, Q7PC89, Q8GZ52

UniProtKB/TrEMBL

A0A178V3Y3

Conserved Domains (6) summary

cd03232
Location:805 → 1035

ABCG_PDR_domain2; Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters

PLN03140
Location:21 → 1400

PLN03140; ABC transporter G family member; Provisional

pfam01061
Location:1130 → 1337

ABC2_membrane; ABC-2 type transporter

pfam08370
Location:709 → 771

PDR_assoc; Plant PDR ABC transporter associated

pfam14510
Location:52 → 138

ABC_trans_N; ABC-transporter extracellular N-terminal

cl21455
Location:131 → 395

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
NM_001341010.1 → NP_001319944.1 pleiotropic drug resistance 2 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

O23376, O23377, Q7PC89, Q8GZ52

UniProtKB/TrEMBL

A0A178V3Y3
NM_001341012.1 → NP_001328801.1 pleiotropic drug resistance 2 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V3Y3, A0A1P8B5S3