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    Aha1 domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820379, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Aha1 domain-containing protein
    Primary source
    TAIR:AT3G12050
    Locus tag
    AT3G12050
    See related
    Araport:AT3G12050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MEC18.18
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (3839101..3841606)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene transmembrane/coiled-coil protein (Protein of unknown function DUF106, transmembrane) Neighboring gene DNA-3-methyladenine glycosylase (MAG) Neighboring gene trichome birefringence-like protein (DUF828) Neighboring gene RAB geranylgeranyl transferase beta subunit 2 Neighboring gene GTP-binding family protein Neighboring gene tetraspanin6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_112039.3
    NM_180235.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Aha1 domain-containing protein
    NP_566410.1
    • Aha1 domain-containing protein; FUNCTIONS IN: ATPase activator activity, chaperone binding; INVOLVED IN: response to stress; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Activator of Hsp90 ATPase, N-terminal (InterPro:IPR015310), Activator of Hsp90 ATPase homologue 1-like (InterPro:IPR013538); Has 600 Blast hits to 579 proteins in 214 species: Archae - 0; Bacteria - 24; Metazoa - 217; Fungi - 180; Plants - 73; Viruses - 0; Other Eukaryotes - 106 (source: NCBI BLink).
    NP_850566.1
    • Aha1 domain-containing protein; FUNCTIONS IN: ATPase activator activity, chaperone binding; INVOLVED IN: response to stress; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Activator of Hsp90 ATPase, N-terminal (InterPro:IPR015310), Activator of Hsp90 ATPase homologue 1-like (InterPro:IPR013538); Has 501 Blast hits to 499 proteins in 203 species: Archae - 0; Bacteria - 24; Metazoa - 214; Fungi - 142; Plants - 65; Viruses - 0; Other Eukaryotes - 56 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3839101..3841606
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112039.3 → NP_566410.1  Aha1 domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566410.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V504, A0A384LMS3, Q8L863, Q9LHL7
      Conserved Domains (2) summary
      cd08892
      Location:225 → 358
      SRPBCC_Aha1; Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins
      pfam09229
      Location:29 → 163
      Aha1_N; Activator of Hsp90 ATPase, N-terminal

    2. NM_180235.1 → NP_850566.1  Aha1 domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850566.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J8L7, Q8L863
      Conserved Domains (3) summary
      cd08892
      Location:186 → 319
      SRPBCC_Aha1; Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins
      COG5580
      Location:20 → 320
      COG5580; Activator of HSP90 ATPase [Posttranslational modification, protein turnover, chaperones]
      pfam09229
      Location:31 → 125
      Aha1_N; Activator of Hsp90 ATPase, N-terminal
    Nucleotide Protein
    Heading Accession and Version

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