Phax phosphorylated adaptor for RNA export [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Phaxprovided by RGD
Official Full Name: phosphorylated adaptor for RNA exportprovided by RGD
Primary source: RGD:708448
See related: EnsemblRapid:ENSRNOG00000014459 AllianceGenome:RGD:708448
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Rnuxa
Summary: Enables toxic substance binding activity. Predicted to be involved in RNA stabilization and snRNA export from nucleus. Located in neuronal cell body. Orthologous to human PHAX (phosphorylated adaptor for RNA export). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 137.9), Brain (RPKM 132.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 18q12.1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (52251231..52267916)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (50053133..50069823)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (51662294..51678981)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH130750 (e-PCR)
- UniSTS:214034

D18Got50 (e-PCR)
- UniSTS:112254

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA cap binding complex binding	ISO Inferred from Sequence Orthology more info
enables toxic substance binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in RNA stabilization	ISO Inferred from Sequence Orthology more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in snRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in snRNA export from nucleus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within snRNA export from nucleus	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Cajal body	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: phosphorylated adapter RNA export protein

Names: 26 kDa resiniferatoxin-binding protein; RBP-2; RBP-26; RNA U small nuclear RNA export adapter protein; RNA U, small nuclear RNA export adaptor; RTX-42; cytosolic resiniferatoxin-binding protein; resiniferatoxin-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.