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    b3gnt2a UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2a [ Danio rerio (zebrafish) ]

    Gene ID: 405766, updated on 9-Dec-2024

    Summary

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    Official Symbol
    b3gnt2aprovided by ZNC
    Official Full Name
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090312-192
    See related
    Ensembl:ENSDARG00000052376 AllianceGenome:ZFIN:ZDB-GENE-090312-192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ssp2; si:ch211-213b8.3
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Orthologous to human B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See b3gnt2a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (53474856..53485604, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (52840215..52850467, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108190370 Neighboring gene zgc:66455 Neighboring gene copper metabolism (Murr1) domain containing 1 Neighboring gene uncharacterized LOC137495827

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2a
    Names
    beta-3-galactosyltransferase (ssp2)
    NP_998005.1
    XP_005160201.1
    XP_005160202.1
    XP_005160203.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212840.1 → NP_998005.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2a

      See identical proteins and their annotated locations for NP_998005.1

      Status: PROVISIONAL

      Source sequence(s)
      AF321828
      UniProtKB/TrEMBL
      A0A8M1PFU7, Q8UWM3
      Related
      ENSDARP00000068710.3, ENSDART00000074221.4
      Conserved Domains (1) summary
      cl21608
      Location:155 → 293
      Galactosyl_T; Galactosyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      53474856..53485604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160144.5 → XP_005160201.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2a isoform X1

      See identical proteins and their annotated locations for XP_005160201.1

      UniProtKB/TrEMBL
      A0A8M2B700
      Conserved Domains (1) summary
      cl21608
      Location:175 → 313
      Galactosyl_T; Galactosyltransferase

    2. XM_005160145.5 → XP_005160202.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2a isoform X1

      See identical proteins and their annotated locations for XP_005160202.1

      UniProtKB/TrEMBL
      A0A8M2B700
      Conserved Domains (1) summary
      cl21608
      Location:175 → 313
      Galactosyl_T; Galactosyltransferase

    3. XM_005160146.5 → XP_005160203.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2a isoform X2

      See identical proteins and their annotated locations for XP_005160203.1

      UniProtKB/TrEMBL
      A0A8M1PFU7, Q8UWM3
      Conserved Domains (1) summary
      cl21608
      Location:155 → 293
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein Strain
    Heading Accession and Version

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