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    ano10a anoctamin 10a [ Danio rerio (zebrafish) ]

    Gene ID: 566425, updated on 9-Dec-2024

    Summary

    Official Symbol
    ano10aprovided by ZNC
    Official Full Name
    anoctamin 10aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050913-43
    See related
    Ensembl:ENSDARG00000057736 AllianceGenome:ZFIN:ZDB-GENE-050913-43
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ano10; fc37b04; wu:fc37b04; zgc:114140
    Summary
    Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 10. Orthologous to human ANO10 (anoctamin 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ano10a in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (7985886..8041348)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (8067642..8125189)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487833 Neighboring gene abhydrolase domain containing 5, lysophosphatidic acid acyltransferase a Neighboring gene SNF related kinase a Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC114140

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chloride channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    anoctamin-10
    Names
    transmembrane protein 16K

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030206.1NP_001025377.1  anoctamin-10

      See identical proteins and their annotated locations for NP_001025377.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097195
      UniProtKB/Swiss-Prot
      Q4V8U5
      Related
      ENSDARP00000112117.1, ENSDART00000126041.2
      Conserved Domains (1) summary
      pfam04547
      Location:200626
      Anoctamin; Calcium-activated chloride channel

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      7985886..8041348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)