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    ipo9 importin 9 [ Danio rerio (zebrafish) ]

    Gene ID: 406860, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ipo9provided by ZNC
    Official Full Name
    importin 9provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2953
    See related
    Ensembl:ENSDARG00000016753 AllianceGenome:ZFIN:ZDB-GENE-040426-2953
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66429; wu:fc23d12
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in protein import into nucleus. Predicted to act upstream of or within intracellular protein transport. Predicted to be active in cytosol and nuclear envelope. Is expressed in several structures, including blood; immature eye; nervous system; ventral mesenchyme; and ventral mesoderm. Orthologous to human IPO9 (importin 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ipo9 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24851671..24875574)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24614018..24639002)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene RAB interacting factor Neighboring gene lysine demethylase 5Ba Neighboring gene shisa family member 4 Neighboring gene leiomodin 1b (smooth muscle)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The orphan G protein-coupled receptor 25 (GPR25) is activated by Apelin and Apela in non-mammalian vertebrates. Zhang J, et al. Biochem Biophys Res Commun, 2018 Jun 22. PMID 29727602
    2. Transcriptional enhancers in protein-coding exons of vertebrate developmental genes. Ritter DI, et al. PLoS One, 2012. PMID 22567096, Free PMC Article
    3. Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis. Recher G, et al. Development, 2013 Dec. PMID 24198278
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    importin-9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213539.1 → NP_998704.1  importin-9

      See identical proteins and their annotated locations for NP_998704.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059203
      UniProtKB/TrEMBL
      Q6PCR2
      Related
      ENSDARP00000137497.1, ENSDART00000167659.2
      Conserved Domains (3) summary
      smart00913
      Location:44 → 118
      IBN_N; Importin-beta N-terminal domain
      COG5657
      Location:35 → 814
      CSE1; CAS/CSE protein involved in chromosome segregation [Cell division and chromosome partitioning]
      sd00044
      Location:518 → 545
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      24851671..24875574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169283.5 → XP_005169340.1  importin-9 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BGJ6
      Conserved Domains (3) summary
      smart00913
      Location:44 → 118
      IBN_N; Importin-beta N-terminal domain
      COG5657
      Location:35 → 813
      CSE1; CAS/CSE protein involved in chromosome segregation [Cell division and chromosome partitioning]
      sd00044
      Location:517 → 544
      HEAT; HEAT repeat [structural motif]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394821.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      33281..56363
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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