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    srpk1b SRSF protein kinase 1b [ Danio rerio (zebrafish) ]

    Gene ID: 791187, updated on 9-Dec-2024

    Summary

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    Official Symbol
    srpk1bprovided by ZNC
    Official Full Name
    SRSF protein kinase 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070112-2292
    See related
    Ensembl:ENSDARG00000031560 AllianceGenome:ZFIN:ZDB-GENE-070112-2292
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:158800
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; regulation of mRNA processing; and spliceosomal complex assembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK1 (SRSF protein kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See srpk1b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (2763168..2828835)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (2693802..2757208)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 167B Neighboring gene mitogen-activated protein kinase 14b Neighboring gene LHFPL tetraspan subfamily member 5a Neighboring gene kinesin family member 21B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SRSF protein kinase 1b
    Names
    serine/arginine-rich protein specific kinase 1b
    NP_001074138.2
    XP_005155715.1
    XP_009304041.1
    XP_068080327.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080669.2 → NP_001074138.2  SRSF protein kinase 1b

      Status: VALIDATED

      Source sequence(s)
      CR318593, CT583672
      UniProtKB/TrEMBL
      A1L2D3
      Related
      ENSDARP00000042971.6, ENSDART00000042972.7

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      2763168..2828835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009305766.4 → XP_009304041.1  SRSF protein kinase 1b isoform X2

      UniProtKB/TrEMBL
      A0A8M3B6N8, A1L2D3
      Conserved Domains (2) summary
      smart00220
      Location:78 → 222
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:68 → 254
      PKc_like; Protein Kinases, catalytic domain

    2. XM_005155658.5 → XP_005155715.1  SRSF protein kinase 1b isoform X1

      UniProtKB/TrEMBL
      A0A8M2B1S0, A1L2D3
      Conserved Domains (2) summary
      smart00220
      Location:80 → 224
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:70 → 256
      PKc_like; Protein Kinases, catalytic domain

    3. XM_068224226.1 → XP_068080327.1  SRSF protein kinase 1b isoform X3

      UniProtKB/TrEMBL
      A0A8M3B3T9
    Nucleotide Protein Strain
    Heading Accession and Version

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