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    gskip gsk3b interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 406744, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gskipprovided by ZNC
    Official Full Name
    gsk3b interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2777
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040426-2777
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55683; wu:fc74a11; wu:fd02b09
    Summary
    Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of Wnt signaling pathway. Predicted to act upstream of or within regulation of canonical Wnt signaling pathway. Predicted to be active in cytoplasm. Orthologous to human GSKIP (GSK3B interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See gskip in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (43012271..43019060)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (43021751..43028522)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene amylase alpha 2A-like 2 Neighboring gene autophagy related 2B Neighboring gene NPC intracellular cholesterol transporter 2, tandem duplicate 2 Neighboring gene NPC intracellular cholesterol transporter 2, tandem duplicate 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Kcnb1 plays a role in development of the inner ear. Jedrychowska J, et al. Dev Biol, 2021 Mar. PMID 33316259
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GSK3-beta interaction protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430894.1 → NP_001417823.1  GSK3-beta interaction protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU929282
      UniProtKB/Swiss-Prot
      Q7ZWI4
      UniProtKB/TrEMBL
      A0A8M2B5T9

    2. NM_213435.2 → NP_998600.2  GSK3-beta interaction protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      CU929282
      UniProtKB/Swiss-Prot
      Q7ZWI4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      43012271..43019060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7ZWI4.1 GenPept UniProtKB/Swiss-Prot:Q7ZWI4

    Gene LinkOut

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