stag1b STAG1 cohesin complex component b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: stag1bprovided by ZNC
Official Full Name: STAG1 cohesin complex component bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1393
See related: Ensembl:ENSDARG00000062137 AllianceGenome:ZFIN:ZDB-GENE-030131-1393
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb69h03; wu:fb69h03; si:ch211-197k23.5
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in sister chromatid cohesion. Predicted to act upstream of or within chromosome segregation. Predicted to be located in chromatin. Predicted to be part of cohesin complex. Predicted to be active in nucleus. Is expressed in head and trunk. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 47. Orthologous to human STAG1 (STAG1 cohesin complex component). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 24

Exon count:: 34

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (26948712..26995161, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (26869497..26916045, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa07e04.r1 (e-PCR)
- UniSTS:189544

fc35c04.x1 (e-PCR)
- UniSTS:188040

fb69h03.x1 (e-PCR)
- UniSTS:203414

fj44c12.y1 (e-PCR)
- UniSTS:199366

fb69h03 (e-PCR)
- UniSTS:187360

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromosome segregation	IEA Inferred from Electronic Annotation more info
involved_in sister chromatid cohesion	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in chromatin	IBA Inferred from Biological aspect of Ancestor more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
part_of cohesin complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cohesin subunit SA-1

Names: stromal antigen 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007135.7 Reference GRCz11 Primary Assembly

Range

26948712..26995161 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_687028.9 → XP_692120.3 cohesin subunit SA-1

UniProtKB/TrEMBL

A0A8N7T7T8, E7FC33

Related

ENSDARP00000120267.1, ENSDART00000142864.2

Conserved Domains (2) summary

COG5537
Location:10 → 394

IRR1; Cohesin [Cell division and chromosome partitioning]

pfam08514
Location:156 → 264

STAG; STAG domain