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    chia.1 chitinase, acidic.1 [ Danio rerio (zebrafish) ]

    Gene ID: 406323, updated on 9-Dec-2024

    Summary

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    Official Symbol
    chia.1provided by ZNC
    Official Full Name
    chitinase, acidic.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1994
    See related
    Ensembl:ENSDARG00000100635 AllianceGenome:ZFIN:ZDB-GENE-040426-1994
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    chit1; zgc:56053; wu:fb57c11; wu:fb66f12
    Summary
    Predicted to enable chitin binding activity and chitinase activity. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in extracellular region. Is expressed in intestinal bulb. Orthologous to human CHIT1 (chitinase 1) and OVGP1 (oviductal glycoprotein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See chia.1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (23993365..23999226)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (23755508..23761369)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490424 Neighboring gene neurofascin homolog (chicken) a Neighboring gene contactin 2 Neighboring gene chitinase, acidic.2 Neighboring gene chitinase, acidic.3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Spatial and temporal expression patterns of chitinase genes in developing zebrafish embryos. Koch BE, et al. Gene Expr Patterns, 2014 Mar. PMID 24418193
    2. Rearing Zebrafish on Black Soldier Fly (Hermetia illucens): Biometric, Histological, Spectroscopic, Biochemical, and Molecular Implications. Vargas A, et al. Zebrafish, 2018 Aug. PMID 29589997
    3. Partial Dietary Inclusion of Hermetia illucens (Black Soldier Fly) Full-Fat Prepupae in Zebrafish Feed: Biometric, Histological, Biochemical, and Molecular Implications. Zarantoniello M, et al. Zebrafish, 2018 Oct. PMID 29912648
    4. Wdr5-mediated H3K4me3 coordinately regulates cell differentiation, proliferation termination, and survival in digestive organogenesis. Zhang Z, et al. Cell Death Discov, 2023 Jul 5. PMID 37407577, Free PMC Article
    5. Thifluzamide induces the toxic effects on zebrafish (Danio rerio) via inhibition of succinate dehydrogenase (SDH). Yang Y, et al. Environ Pollut, 2020 Oct. PMID 32806454

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    chitinase, acidic.1
    Names
    chia1
    NP_998215.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213050.1 → NP_998215.1  chitinase, acidic.1 precursor

      See identical proteins and their annotated locations for NP_998215.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045887
      UniProtKB/TrEMBL
      B2GT22, Q7ZVF1
      Related
      ENSDARP00000139296.1, ENSDART00000172459.2
      Conserved Domains (3) summary
      cd02872
      Location:24 → 386
      GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...
      smart00494
      Location:407 → 455
      ChtBD2; Chitin-binding domain type 2
      smart00636
      Location:23 → 364
      Glyco_18; Glyco_18 domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      23993365..23999226
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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