matn4 matrilin 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: matn4provided by ZNC
Official Full Name: matrilin 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-050208-64
See related: Ensembl:ENSDARG00000015947 AllianceGenome:ZFIN:ZDB-GENE-050208-64
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7137546; matrilin-4
Summary: Predicted to enable magnesium ion binding activity. Predicted to be involved in system development. Predicted to be active in collagen-containing extracellular matrix. Is expressed in several structures, including hypochord; integument; nervous system; skeletal system; and vertical myoseptum. Orthologous to several human genes including MATN4 (matrilin 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (52789915..52846146)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (52791516..52847817)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in system development	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: matrilin-4

Names: matrilin-4-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213549.1 → NP_998714.1 matrilin-4 precursor

See identical proteins and their annotated locations for NP_998714.1

Status: PROVISIONAL

Source sequence(s)

AY570730

UniProtKB/TrEMBL

A0A8M1PQH4, A0A8M2B1W5, A0A8M9PZP8, F1Q7C5, Q6PYX2

Related

ENSDARP00000021634.9, ENSDART00000002571.10

Conserved Domains (2) summary

pfam14670
Location:258 → 293

FXa_inhibition; Coagulation Factor Xa inhibitory site

cl00057
Location:588 → 821

vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...