gnl3l G protein nucleolar 3 like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gnl3lprovided by ZNC
Official Full Name: G protein nucleolar 3 likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040723-1
See related: Ensembl:ENSDARG00000020595 AllianceGenome:ZFIN:ZDB-GENE-040723-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: flj10613; flj10613l; zgc:110536; SI:zK13A21.8; si:dkey-13a21.8
Summary: Predicted to enable GTP binding activity. Acts upstream of or within rRNA processing. Predicted to be active in nucleolus. Orthologous to human GNL3L (G protein nucleolar 3 like). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (25485774..25502490)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (25248158..25264874)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within rRNA processing	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: guanine nucleotide-binding protein-like 3-like protein

Names: guanine nucleotide binding protein-like 3 (nucleolar)-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002875.1 → NP_001002875.1 guanine nucleotide-binding protein-like 3-like protein

See identical proteins and their annotated locations for NP_001002875.1

Status: PROVISIONAL

Source sequence(s)

AY648737

UniProtKB/TrEMBL

F6PBQ3, Q6DRM2, Q7SZX9

Related

ENSDARP00000005405.6, ENSDART00000026249.7

Conserved Domains (4) summary

cd04178
Location:127 → 298

Nucleostemin_like; A circularly permuted subfamily of the Ras GTPases

COG1161
Location:92 → 397

RbgA; Ribosome biogenesis GTPase A [Translation, ribosomal structure and biogenesis]

pfam08701
Location:2 → 69

GN3L_Grn1; GNL3L/Grn1 putative GTPase

cl21455
Location:249 → 357

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases