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    pbxip1b pre-B-cell leukemia homeobox interacting protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 553293, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pbxip1bprovided by ZNC
    Official Full Name
    pre-B-cell leukemia homeobox interacting protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070112-2032
    See related
    Ensembl:ENSDARG00000011824 AllianceGenome:ZFIN:ZDB-GENE-070112-2032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7138234; wu:fb12b01; zgc:158151
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human PBXIP1 (PBX homeobox interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See pbxip1b in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (22750174..22775501, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (22834779..22860138, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene toll-like receptor 19, tandem duplicate 1 Neighboring gene toll-like receptor 13 Neighboring gene lens epithelial protein Neighboring gene SHC (Src homology 2 domain containing) transforming protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. Takeuchi M, et al. J Comp Neurol, 2017 May 1. PMID 27615194
    2. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC158151

    General protein information

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    Preferred Names
    pre-B-cell leukemia homeobox interacting protein 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079956.2 → NP_001073425.2  pre-B-cell leukemia homeobox interacting protein 1b

      Status: VALIDATED

      Source sequence(s)
      CR854942
      UniProtKB/TrEMBL
      A0A8M1NCC8, E7F6R0
      Related
      ENSDARP00000110994.2, ENSDART00000127570.4
      Conserved Domains (1) summary
      PTZ00121
      Location:326 → 678
      PTZ00121; MAEBL; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      22750174..22775501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017351348.3 → XP_017206837.1  pre-B-cell leukemia homeobox interacting protein 1b isoform X2

      UniProtKB/TrEMBL
      A0A8M6Z1S6

    2. XM_021466689.2 → XP_021322364.1  pre-B-cell leukemia homeobox interacting protein 1b isoform X1

      UniProtKB/TrEMBL
      A0A8M9PD37
      Conserved Domains (1) summary
      cl26511
      Location:334 → 686
      Neuromodulin_N; Gap junction protein N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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