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    ndc1 NDC1 transmembrane nucleoporin [ Danio rerio (zebrafish) ]

    Gene ID: 335236, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ndc1provided by ZNC
    Official Full Name
    NDC1 transmembrane nucleoporinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7176
    See related
    Ensembl:ENSDARG00000021120 AllianceGenome:ZFIN:ZDB-GENE-030131-7176
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tmem48; zgc:55636; wu:fk93f04
    Summary
    Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in nuclear pore organization. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore transmembrane ring. Orthologous to human NDC1 (NDC1 transmembrane nucleoporin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ndc1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (26576856..26590561, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (26921201..26935097, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene si:ch211-106k21.5 Neighboring gene zinc finger protein GLIS1 Neighboring gene uncharacterized LOC101883238 Neighboring gene zgc:113691 Neighboring gene Yip1 domain family, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish. Zhong Y, et al. Nucleic Acids Res, 2018 Apr 20. PMID 29447387, Free PMC Article
    2. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nuclear pore organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nuclear pore transmembrane ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nucleoporin NDC1
    Names
    transmembrane protein 48

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199943.1 → NP_956237.1  nucleoporin NDC1

      See identical proteins and their annotated locations for NP_956237.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053915
      UniProtKB/Swiss-Prot
      Q7SZC5
      Related
      ENSDARP00000016349.8, ENSDART00000025120.9
      Conserved Domains (1) summary
      pfam09531
      Location:13 → 663
      Ndc1_Nup; Nucleoporin protein Ndc1-Nup

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      26576856..26590561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009298544.4 → XP_009296819.1  nucleoporin NDC1 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AXA1
      Conserved Domains (1) summary
      pfam09531
      Location:13 → 646
      Ndc1_Nup; Nucleoporin protein Ndc1-Nup
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7SZC5.1 GenPept UniProtKB/Swiss-Prot:Q7SZC5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.