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    bzw1a basic leucine zipper and W2 domains 1a [ Danio rerio (zebrafish) ]

    Gene ID: 325226, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bzw1aprovided by ZNC
    Official Full Name
    basic leucine zipper and W2 domains 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3951
    See related
    Ensembl:ENSDARG00000010481 AllianceGenome:ZFIN:ZDB-GENE-030131-3951
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    bzw1; zgc:63787; wu:fc60e05
    Summary
    Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm. Is expressed in eye; forebrain; immature eye; neural plate; and presumptive neural plate. Orthologous to human BZW1 (basic leucine zipper and W2 domains 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See bzw1a in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (14117091..14126065)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (14092314..14101288)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene aldehyde oxidase 5 Neighboring gene hatching enzyme 1, tandem dupliate 2 Neighboring gene si:ch211-246m6.4 Neighboring gene hatching enzyme 1, tandem duplicate 3 Neighboring gene si:ch211-246m6.5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of zebrafish ocular formation genes. Wang H, et al. Genome, 2008 Mar. PMID 18356958
    2. Analysis of the exon-intron structures of fish, amphibian, bird and mammalian hatching enzyme genes, with special reference to the intron loss evolution of hatching enzyme genes in Teleostei. Kawaguchi M, et al. Gene, 2007 May 1. PMID 17222522
    3. Identification of differentially expressed genes between cloned and zygote-developing zebrafish (Danio rerio) embryos at the dome stage using suppression subtractive hybridization. Luo D, et al. Biol Reprod, 2009 Apr. PMID 19092113
    4. Identification of nodal signaling targets by array analysis of induced complex probes. Dickmeis T, et al. Dev Dyn, 2001 Dec. PMID 11748827
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    eIF5-mimic protein 2-A
    Names
    basic leucine zipper and W2 domain-containing protein 1-A
    basic leucine zipper and W2 domains 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199708.1 → NP_956002.1  eIF5-mimic protein 2-A

      See identical proteins and their annotated locations for NP_956002.1

      Status: PROVISIONAL

      Source sequence(s)
      BC058875
      UniProtKB/Swiss-Prot
      Q6PD83
      Related
      ENSDARP00000022789.6, ENSDART00000013575.7
      Conserved Domains (1) summary
      cd11560
      Location:217 → 407
      W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      14117091..14126065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PD83.1 GenPept UniProtKB/Swiss-Prot:Q6PD83

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