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    etaa1b ETAA1 activator of ATR kinase b [ Danio rerio (zebrafish) ]

    Gene ID: 100005357, updated on 9-Dec-2024

    Summary

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    Official Symbol
    etaa1bprovided by ZNC
    Official Full Name
    ETAA1 activator of ATR kinase bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081107-73
    See related
    Ensembl:ENSDARG00000078166 AllianceGenome:ZFIN:ZDB-GENE-081107-73
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-78p8.1; si:dkey-78p8.2
    Summary
    Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in DNA damage response; regulation of DNA damage checkpoint; and replication fork processing. Predicted to be active in nuclear replication fork. Orthologous to human ETAA1 (ETAA1 activator of ATR kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See etaa1b in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (5245099..5257520, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (5118673..5128966, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family G (WHITE), member 2c Neighboring gene solute carrier family 29 member 3 Neighboring gene uncharacterized LOC137487358 Neighboring gene uncharacterized LOC137487359

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Tetraodon nigroviridis reference transcriptome: developmental transition, length retention and microsynteny of long non-coding RNAs in a compact vertebrate genome. Basu S, et al. Sci Rep, 2016 Sep 15. PMID 27628538, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    equilibrative nucleoside transporter 3; ewing's tumor-associated antigen 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      5245099..5257520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480714.2 → XP_021336389.1  ewing's tumor-associated antigen 1

      UniProtKB/TrEMBL
      A0A8M1Q7V8
      Related
      ENSDARP00000131929.1, ENSDART00000110610.4
      Conserved Domains (1) summary
      pfam15350
      Location:59 → 455
      ETAA1; Ewing's tumor-associated antigen 1 homolog

    RNA

    1. XR_011005882.1 RNA Sequence

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394862.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      52694..65115 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001344402.9 → XP_001344438.6  ewing's tumor-associated antigen 1

      UniProtKB/TrEMBL
      A0A8M1Q7V8
      Conserved Domains (1) summary
      pfam15350
      Location:59 → 455
      ETAA1; Ewing's tumor-associated antigen 1 homolog

    RNA

    1. XR_011009930.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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