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    mindy4b MINDY family member 4B [ Danio rerio (zebrafish) ]

    Gene ID: 569648, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mindy4bprovided by ZNC
    Official Full Name
    MINDY family member 4Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-140127-1
    See related
    Ensembl:ENSDARG00000112337 AllianceGenome:ZFIN:ZDB-GENE-140127-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam188b2
    Summary
    Predicted to enable K48-linked deubiquitinase activity. Predicted to act upstream of or within protein K48-linked deubiquitination and proteolysis. Is expressed in neuromast. Orthologous to human MINDY4B (MINDY family member 4B). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See mindy4b in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (3926907..3940134, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RNF14-like Neighboring gene zmp:0000001236 Neighboring gene clarin 1 Neighboring gene G protein-coupled receptor 171

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007126.7 Chromosome 15 Reference GRCz11 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification of sensory hair-cell transcripts by thiouracil-tagging in zebrafish. Erickson T, et al. BMC Genomics, 2015 Oct 23. PMID 26494580, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables K48-linked deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B
    Names
    family with sequence similarity 188, member B2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      3926907..3940134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021466306.2 → XP_021321981.1  inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B

      UniProtKB/TrEMBL
      A0A8M9PIC2
      Related
      ENSDARP00000155481.1, ENSDART00000189741.1
      Conserved Domains (1) summary
      pfam13898
      Location:117 → 468
      DUF4205; Domain of unknown function (DUF4205)
    Nucleotide Protein Strain
    Heading Accession and Version

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