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    faimb Fas apoptotic inhibitory molecule b [ Danio rerio (zebrafish) ]

    Gene ID: 436668, updated on 9-Dec-2024

    Summary

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    Official Symbol
    faimbprovided by ZNC
    Official Full Name
    Fas apoptotic inhibitory molecule bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-91
    See related
    Ensembl:ENSDARG00000020814 AllianceGenome:ZFIN:ZDB-GENE-040718-91
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92712
    Summary
    Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Predicted to act upstream of or within negative regulation of apoptotic process. Is expressed in epiphysis and retinal photoreceptor layer. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See faimb in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (16400049..16406213, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (16273104..16279270, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene gastrulation brain homeobox 2 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 Neighboring gene coiled-coil domain containing 80 like 1 Neighboring gene solute carrier family 19 member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Fas apoptotic inhibitory molecule b; fas apoptotic inhibitory molecule b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002395.2 → NP_001002395.1  Fas apoptotic inhibitory molecule b

      See identical proteins and their annotated locations for NP_001002395.1

      Status: VALIDATED

      Source sequence(s)
      CR854926
      UniProtKB/TrEMBL
      A0A8M1N0G7, Q6DGZ2
      Related
      ENSDARP00000008711.7, ENSDART00000012023.8
      Conserved Domains (1) summary
      pfam06905
      Location:4 → 175
      FAIM1; Fas apoptotic inhibitory molecule (FAIM1)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      16400049..16406213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168710.5 → XP_005168767.1  fas apoptotic inhibitory molecule b isoform X1

      UniProtKB/TrEMBL
      A0A8M2BG05
      Conserved Domains (1) summary
      pfam06905
      Location:4 → 177
      FAIM1; Fas apoptotic inhibitory molecule (FAIM1)
    Nucleotide Protein
    Heading Accession and Version

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