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    fryl furry homolog, like [ Danio rerio (zebrafish) ]

    Gene ID: 558173, updated on 9-Dec-2024

    Summary

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    Official Symbol
    frylprovided by ZNC
    Official Full Name
    furry homolog, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040914-58
    See related
    Ensembl:ENSDARG00000040001 AllianceGenome:ZFIN:ZDB-GENE-040914-58
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc84g03; im:6912409; wu:fc84g03; si:dkey-90m5.7
    Summary
    Acts upstream of or within heart development. Predicted to be active in cell cortex and site of polarized growth. Orthologous to human FRYL (FRY like transcription coactivator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See fryl in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    65
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (23254455..23422345)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (23355348..23523245)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene OCIA domain containing 2 Neighboring gene OCIA domain containing 1 Neighboring gene si:dkey-90m5.4 Neighboring gene solute carrier family 10 member 4 Neighboring gene zygote arrest 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Global gene expression analysis reveals dynamic and developmental stage-dependent enrichment of lead-induced neurological gene alterations. Peterson SM, et al. Environ Health Perspect, 2011 May. PMID 21147602, Free PMC Article
    2. Large-scale discovery of novel genetic causes of developmental disorders. Deciphering Developmental Disorders Study. Nature, 2015 Mar 12. PMID 25533962, Free PMC Article
    3. prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish. Wang Y, et al. J Genet Genomics, 2018 Aug 20. PMID 30174136
    4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein furry homolog-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159667.1 → NP_001153139.1  protein furry homolog-like

      Status: PROVISIONAL

      Source sequence(s)
      BX323889, BX537133
      UniProtKB/TrEMBL
      A0A8M1NSS1, A0A8M3ALH6, B8JMD7
      Related
      ENSDARP00000115658.1, ENSDART00000132248.3
      Conserved Domains (3) summary
      pfam14222
      Location:173 → 705
      MOR2-PAG1_N; Cell morphogenesis N-terminal
      pfam14225
      Location:2069 → 2322
      MOR2-PAG1_C; Cell morphogenesis C-terminal
      pfam14228
      Location:743 → 1921
      MOR2-PAG1_mid; Cell morphogenesis central region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      23254455..23422345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068215473.1 → XP_068071574.1  protein furry homolog-like isoform X7

      UniProtKB/TrEMBL
      A0A8M2B7D4

    2. XM_068215468.1 → XP_068071569.1  protein furry homolog-like isoform X1

      UniProtKB/TrEMBL
      A0A8M2B7D4

    3. XM_068215469.1 → XP_068071570.1  protein furry homolog-like isoform X2

      UniProtKB/TrEMBL
      A0A8M2B7D4

    4. XM_068215471.1 → XP_068071572.1  protein furry homolog-like isoform X5

      UniProtKB/TrEMBL
      A0A8M2B7D4

    5. XM_005160537.5 → XP_005160594.2  protein furry homolog-like isoform X4

      UniProtKB/TrEMBL
      A0A8M2B7D4

    6. XM_068215472.1 → XP_068071573.1  protein furry homolog-like isoform X6

      UniProtKB/TrEMBL
      A0A8M2B7D4

    7. XM_068215470.1 → XP_068071571.1  protein furry homolog-like isoform X3

      UniProtKB/TrEMBL
      A0A8M2B7D4

    8. XM_009294673.4 → XP_009292948.2  protein furry homolog-like isoform X9

      UniProtKB/TrEMBL
      A0A8M2B7D4

    9. XM_009294672.4 → XP_009292947.2  protein furry homolog-like isoform X8

      UniProtKB/TrEMBL
      A0A8M2B7D4
    Nucleotide Protein
    Heading Accession and Version

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