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    osbpl9 oxysterol binding protein-like 9 [ Danio rerio (zebrafish) ]

    Gene ID: 777767, updated on 9-Dec-2024

    Summary

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    Official Symbol
    osbpl9provided by ZNC
    Official Full Name
    oxysterol binding protein-like 9provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061110-103
    See related
    Ensembl:ENSDARG00000069298 AllianceGenome:ZFIN:ZDB-GENE-061110-103
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:154069
    Summary
    Predicted to enable sterol binding activity. Predicted to act upstream of or within lipid transport. Predicted to be active in Golgi apparatus; cytosol; and membrane. Orthologous to human OSBPL9 (oxysterol binding protein like 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See osbpl9 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (16615798..16674588, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (16580086..16638887, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD75 Neighboring gene small nucleolar RNA SNORD74 Neighboring gene growth arrest specific 5 Neighboring gene si:ch211-198n5.11 Neighboring gene retinoid isomerohydrolase RPE65 b Neighboring gene retinoid isomerohydrolase RPE65 c

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility. Goudarzi M, et al. Elife, 2019 Jan 8. PMID 30620332, Free PMC Article
    2. A vertebrate model for the study of lipid binding/transfer protein function: conservation of OSBP-related proteins between zebrafish and human. Zhou Y, et al. Biochem Biophys Res Commun, 2014 Apr 11. PMID 24326072
    3. Systematic Identification of Long Noncoding RNAs during Three Key Organogenesis Stages in Zebrafish. Zhou C, et al. Int J Mol Sci, 2024 Mar 19. PMID 38542412, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sterol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    oxysterol-binding protein-related protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077805.1 → NP_001071273.1  oxysterol-binding protein-related protein 9

      See identical proteins and their annotated locations for NP_001071273.1

      Status: PROVISIONAL

      Source sequence(s)
      BC125949
      UniProtKB/TrEMBL
      A0A8M1NC31, A0A8M3AV09, A0JMN8
      Related
      ENSDARP00000091500.4, ENSDART00000100727.6
      Conserved Domains (4) summary
      PHA02664
      Location:272 → 370
      PHA02664; hypothetical protein; Provisional
      cd13290
      Location:5 → 106
      PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
      pfam00169
      Location:4 → 98
      PH; PH domain
      pfam01237
      Location:377 → 725
      Oxysterol_BP; Oxysterol-binding protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      16615798..16674588 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009303857.4 → XP_009302132.1  oxysterol-binding protein-related protein 9 isoform X1

      UniProtKB/TrEMBL
      A0A2R8Q9E0, A0A8M3AV09, A0A8M3BBP2
      Related
      ENSDARP00000149759.1, ENSDART00000191982.1
      Conserved Domains (4) summary
      PHA02664
      Location:259 → 357
      PHA02664; hypothetical protein; Provisional
      cd13290
      Location:5 → 106
      PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
      pfam00169
      Location:4 → 98
      PH; PH domain
      pfam01237
      Location:364 → 712
      Oxysterol_BP; Oxysterol-binding protein

    2. XM_005166901.5 → XP_005166958.1  oxysterol-binding protein-related protein 9 isoform X3

      UniProtKB/TrEMBL
      A0A8M2BEE5, A0A8M3AV09
      Conserved Domains (2) summary
      pfam01237
      Location:213 → 561
      Oxysterol_BP; Oxysterol-binding protein
      pfam17037
      Location:10 → 167
      CBP_BcsO; Cellulose biosynthesis protein BcsO

    3. XM_005166900.5 → XP_005166957.1  oxysterol-binding protein-related protein 9 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BEE1, A0A8M3AV09
      Conserved Domains (2) summary
      PHA02664
      Location:175 → 273
      PHA02664; hypothetical protein; Provisional
      pfam01237
      Location:280 → 628
      Oxysterol_BP; Oxysterol-binding protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394716.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      6598..27386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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