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    BC028528 cDNA sequence BC028528 [ Mus musculus (house mouse) ]

    Gene ID: 229600, updated on 27-Nov-2024

    Summary

    Official Symbol
    BC028528provided by MGI
    Official Full Name
    cDNA sequence BC028528provided by MGI
    Primary source
    MGI:MGI:2385885
    See related
    Ensembl:ENSMUSG00000038543 AllianceGenome:MGI:2385885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L259
    Summary
    Acts upstream of or within epithelial cell proliferation involved in renal tubule morphogenesis; phosphatidylinositol 3-kinase/protein kinase B signal transduction; and response to wounding. Predicted to be located in extracellular region. Orthologous to human C1orf54 (chromosome 1 open reading frame 54). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in lung adult (RPKM 15.9), bladder adult (RPKM 3.2) and 21 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See BC028528 in Genome Data Viewer
    Location:
    3 F2.1; 3 41.44 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95789665..95800186, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95883945..95892062, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E10199 Neighboring gene RIKEN cDNA C920021L13 gene Neighboring gene mitochondrial ribosomal protein S21 Neighboring gene STARR-positive B cell enhancer ABC_E9562 Neighboring gene circadian associated repressor of transcription Neighboring gene STARR-positive B cell enhancer ABC_E2673 Neighboring gene aph1 homolog A, gamma secretase subunit Neighboring gene carbonic anhydrase 14 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:95732686-95732932 Neighboring gene predicted gene, 46815

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (3)  1 citation

    General protein information

    Preferred Names
    uncharacterized protein C1orf54 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001346514.2NP_001333443.1  uncharacterized protein C1orf54 homolog isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AC092855
      Consensus CDS
      CCDS84656.1
      UniProtKB/Swiss-Prot
      Q8R2K8
      Related
      ENSMUSP00000046810.7, ENSMUST00000036360.13
      Conserved Domains (1) summary
      pfam15465
      Location:1145
      DUF4634; Domain of unknown function (DUF4634)
    2. NM_001399777.1NP_001386706.1  uncharacterized protein C1orf54 homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC092855
    3. NM_153513.4NP_705733.2  uncharacterized protein C1orf54 homolog isoform 1 precursor

      See identical proteins and their annotated locations for NP_705733.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC092855
      Consensus CDS
      CCDS50998.1
      UniProtKB/Swiss-Prot
      Q8K3T8, Q8R2K8
      Related
      ENSMUSP00000102749.2, ENSMUST00000090476.10
      Conserved Domains (1) summary
      pfam15465
      Location:1146
      DUF4634; Domain of unknown function (DUF4634)

    RNA

    1. NR_166867.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC092855
    2. NR_166868.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC092855

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      95789665..95800186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163066.1XP_036018959.1  uncharacterized protein C1orf54 homolog isoform X3

      Conserved Domains (1) summary
      pfam15465
      Location:1106
      DUF4634; Domain of unknown function (DUF4634)
    2. XM_006501379.2XP_006501442.1  uncharacterized protein C1orf54 homolog isoform X4

      Conserved Domains (1) summary
      pfam15465
      Location:1141
      DUF4634; Domain of unknown function (DUF4634)
    3. XM_036163065.1XP_036018958.1  uncharacterized protein C1orf54 homolog isoform X2

      Conserved Domains (1) summary
      pfam15465
      Location:698
      DUF4634; Domain of unknown function (DUF4634)
    4. XM_011240095.4XP_011238397.1  uncharacterized protein C1orf54 homolog isoform X1

      Conserved Domains (1) summary
      pfam15465
      Location:1106
      DUF4634; Domain of unknown function (DUF4634)