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    S100pbp S100P binding protein [ Mus musculus (house mouse) ]

    Gene ID: 74648, updated on 9-Dec-2024

    Summary

    Official Symbol
    S100pbpprovided by MGI
    Official Full Name
    S100P binding proteinprovided by MGI
    Primary source
    MGI:MGI:1921898
    See related
    Ensembl:ENSMUSG00000040928 AllianceGenome:MGI:1921898
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S100pbpr; 4930429A08Rik
    Summary
    Predicted to enable calcium-dependent protein binding activity. Predicted to be located in nuclear speck. Predicted to be active in cytosol and nucleus. Orthologous to human S100PBP (S100P binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 14.2), CNS E11.5 (RPKM 9.5) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See S100pbp in Genome Data Viewer
    Location:
    4 D2.2; 4 62.96 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129041795..129083485, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129148002..129189665, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 54 Neighboring gene STARR-positive B cell enhancer ABC_E4669 Neighboring gene hippocalcin Neighboring gene fibronectin type III domain containing 5 Neighboring gene STARR-positive B cell enhancer ABC_E3517 Neighboring gene STARR-seq mESC enhancer starr_11478 Neighboring gene tyrosyl-tRNA synthetase 1 Neighboring gene STARR-seq mESC enhancer starr_11480 Neighboring gene NHS like 3 Neighboring gene STARR-seq mESC enhancer starr_11482 Neighboring gene predicted gene 12976

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347203.2NP_001334132.1  S100P-binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 9 and 10, encodes isoform 2.
      Source sequence(s)
      AL606977
      Consensus CDS
      CCDS84797.1
      UniProtKB/Swiss-Prot
      Q9D5K4
      Related
      ENSMUSP00000101674.2, ENSMUST00000106059.8
      Conserved Domains (1) summary
      pfam15427
      Location:21263
      S100PBPR; S100P-binding protein
    2. NM_001361317.2NP_001348246.1  S100P-binding protein isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variant 11, encodes isoform 3.
      Source sequence(s)
      AL606977
      Consensus CDS
      CCDS89830.1
      UniProtKB/TrEMBL
      E9Q5M3
      Related
      ENSMUSP00000072258.7, ENSMUST00000072431.13
      Conserved Domains (1) summary
      pfam15427
      Location:21304
      S100PBPR; S100P-binding protein
    3. NM_001379588.1NP_001366517.1  S100P-binding protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 4-8 all encode the same isoform (1).
      Source sequence(s)
      AL606977
      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein
    4. NM_001379589.1NP_001366518.1  S100P-binding protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 1, 4, and 6-8, encodes isoform 1.
      Source sequence(s)
      AL606977
      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein
    5. NM_001379590.1NP_001366519.1  S100P-binding protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 1, 4, 5, 7, and 8, encodes isoform 1.
      Source sequence(s)
      AL606977
      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein
    6. NM_001379591.1NP_001366520.1  S100P-binding protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 1, 4-6, and 8, encodes isoform 1.
      Source sequence(s)
      AL606977
      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Related
      ENSMUSP00000039820.6, ENSMUST00000049081.12
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein
    7. NM_001379592.1NP_001366521.1  S100P-binding protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variants 1 and 4-7, encodes isoform 1.
      Source sequence(s)
      AL606977
      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein
    8. NM_001379593.1NP_001366522.1  S100P-binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9), as well as variants 2 and 10, encodes isoform 2.
      Source sequence(s)
      AL606977
      Conserved Domains (1) summary
      pfam15427
      Location:21263
      S100PBPR; S100P-binding protein
    9. NM_001379594.1NP_001366523.1  S100P-binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variants 2 and 9, encodes isoform 2.
      Source sequence(s)
      AL606977
      Conserved Domains (1) summary
      pfam15427
      Location:21263
      S100PBPR; S100P-binding protein
    10. NM_001379595.1NP_001366524.1  S100P-binding protein isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variant 3, encodes isoform 3.
      Source sequence(s)
      AL606977
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21304
      S100PBPR; S100P-binding protein
    11. NM_001379596.1NP_001366525.1  S100P-binding protein isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variants 13 and 14, encodes isoform 4.
      Source sequence(s)
      AL606977
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21340
      S100PBPR; S100P-binding protein
    12. NM_001379597.1NP_001366526.1  S100P-binding protein isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13), as well as variants 12 and 14, encodes isoform 4.
      Source sequence(s)
      AL606977
      UniProtKB/TrEMBL
      E9Q5M3
      Related
      ENSMUSP00000113084.2, ENSMUST00000117497.8
      Conserved Domains (1) summary
      pfam15427
      Location:21340
      S100PBPR; S100P-binding protein
    13. NM_001379598.1NP_001366527.1  S100P-binding protein isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14), as well as variants 12 and 13, encodes isoform 4.
      Source sequence(s)
      AL606977
      UniProtKB/TrEMBL
      E9Q5M3
      Related
      ENSMUSP00000113920.2, ENSMUST00000117965.8
      Conserved Domains (1) summary
      pfam15427
      Location:21340
      S100PBPR; S100P-binding protein
    14. NM_001379599.1NP_001366528.1  S100P-binding protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL606977
      Conserved Domains (1) summary
      pfam15427
      Location:21305
      S100PBPR; S100P-binding protein
    15. NM_029036.4NP_083312.1  S100P-binding protein isoform 1

      See identical proteins and their annotated locations for NP_083312.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 4. Variants 1 and 4-8 all encode the same isoform (1).
      Source sequence(s)
      AL606977
      Consensus CDS
      CCDS18684.1
      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Related
      ENSMUSP00000101676.3, ENSMUST00000106061.9
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      129041795..129083485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503448.4XP_006503511.1  S100P-binding protein isoform X1

      See identical proteins and their annotated locations for XP_006503511.1

      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein
    2. XM_036164504.1XP_036020397.1  S100P-binding protein isoform X2

      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21346
      S100PBPR; S100P-binding protein
    3. XM_036164507.1XP_036020400.1  S100P-binding protein isoform X4

      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21304
      S100PBPR; S100P-binding protein
    4. XM_036164505.1XP_036020398.1  S100P-binding protein isoform X3

      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21340
      S100PBPR; S100P-binding protein
    5. XM_036164506.1XP_036020399.1  S100P-binding protein isoform X4

      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21304
      S100PBPR; S100P-binding protein
    6. XM_006503446.5XP_006503509.1  S100P-binding protein isoform X1

      See identical proteins and their annotated locations for XP_006503509.1

      UniProtKB/Swiss-Prot
      A2A7S5, Q3UJU0, Q3UTU1, Q3V367, Q8BSS8, Q8C925, Q8CHX8, Q9D5K4
      UniProtKB/TrEMBL
      E9Q5M3
      Conserved Domains (1) summary
      pfam15427
      Location:21382
      S100PBPR; S100P-binding protein