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    SDP1 Patatin-like phospholipase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830283, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SDP1
    Official Full Name
    Patatin-like phospholipase family protein
    Primary source
    TAIR:AT5G04040
    Locus tag
    AT5G04040
    See related
    Araport:AT5G04040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F8F6.250; F8F6_250; SUGAR-DEPENDENT1
    Summary
    Encodes a triacylglycerol lipase that is involved in storage lipid breakdown during seed germination. The mutant plant exhibits a much slower rate of postgerminative growth than the wild type.
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    Genomic context

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    See SDP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (1089342..1093204)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene calmodulin binding protein Neighboring gene uncharacterized protein Neighboring gene Putative membrane lipoprotein Neighboring gene Plant self-incompatibility protein S1 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Central Role for Triacylglycerol in Membrane Lipid Breakdown, Fatty Acid β-Oxidation, and Plant Survival under Extended Darkness. Fan J, et al. Plant Physiol, 2017 Jul. PMID 28572457, Free PMC Article
    2. Peroxisome extensions deliver the Arabidopsis SDP1 lipase to oil bodies. Thazar-Poulot N, et al. Proc Natl Acad Sci U S A, 2015 Mar 31. PMID 25775518, Free PMC Article
    3. The sugar-dependent1 lipase limits triacylglycerol accumulation in vegetative tissues of Arabidopsis. Kelly AA, et al. Plant Physiol, 2013 Jul. PMID 23686420, Free PMC Article
    4. Suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase family during seed development enhances oil yield in oilseed rape (Brassica napus L.). Kelly AA, et al. Plant Biotechnol J, 2013 Apr. PMID 23171303
    5. Arabidopsis lipins, PDAT1 acyltransferase, and SDP1 triacylglycerol lipase synergistically direct fatty acids toward β-oxidation, thereby maintaining membrane lipid homeostasis. Fan J, et al. Plant Cell, 2014 Oct. PMID 25293755, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that PHOSPHOLIPID:DIACYLGLYCEROL ACYLTRANSFERASE1 (PDAT1) and SUGAR-DEPENDENT1 (SDP1) TAG lipase, function synergistically in directing fatty acids (FAs) toward peroxisomal beta-oxidation via triacylglycerol (TAG) intermediates.
      Title: Arabidopsis lipins, PDAT1 acyltransferase, and SDP1 triacylglycerol lipase synergistically direct fatty acids toward β-oxidation, thereby maintaining membrane lipid homeostasis.
    2. Arabidopsis SDP1 lipase is delivered to oil bodies by peroxisome extensions
      Title: Peroxisome extensions deliver the Arabidopsis SDP1 lipase to oil bodies.
    3. SDP1 limits triacylglycerol accumulation in vegetative tissues of Arabidopsis.
      Title: The sugar-dependent1 lipase limits triacylglycerol accumulation in vegetative tissues of Arabidopsis.
    4. RNAi suppression during seed development results in a gain in oil yield
      Title: Suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase family during seed development enhances oil yield in oilseed rape (Brassica napus L.).
    5. together SDP1 and SDP1L account for at least 95% of the rate of triacylglycerol hydrolysis in Arabidopsis seeds, and that this hydrolysis is important but not essential for seed germination or seedling establishment.
      Title: Seed storage oil mobilization is important but not essential for germination or seedling establishment in Arabidopsis.
    6. SDP1 encodes a lipase that initiates oil breakdown in germinating Arabidopsis seeds. [SDP1]
      Title: SUGAR-DEPENDENT1 encodes a patatin domain triacylglycerol lipase that initiates storage oil breakdown in germinating Arabidopsis seeds.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001342744.1
    NM_120486.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables triacylglycerol lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables triacylglycerol lipase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within triglyceride catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in triglyceride catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within triglyceride metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in monolayer-surrounded lipid storage body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Patatin-like phospholipase family protein
    NP_196024.1
    • SUGAR-DEPENDENT1 (SDP1); CONTAINS InterPro DOMAIN/s: Acyl transferase/acyl hydrolase/lysophospholipase (InterPro:IPR016035), Protein of unknown function DUF3336 (InterPro:IPR021771), ARF/SAR superfamily (InterPro:IPR006689), Patatin (InterPro:IPR002641); BEST Arabidopsis thaliana protein match is: sugar-dependent 1-like (TAIR:AT3G57140.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1089342..1093204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120486.7 → NP_196024.1  Patatin-like phospholipase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56WV8, Q9LZA6
      UniProtKB/TrEMBL
      A0A178UB07, A0A5S9Y223
      Conserved Domains (2) summary
      cd07231
      Location:162 → 571
      Pat_SDP1-like; Sugar-Dependent 1 like lipase
      pfam11815
      Location:96 → 225
      DUF3336; Domain of unknown function (DUF3336)

    2. NM_001342744.1 → NP_001332745.1  Patatin-like phospholipase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56WV8, Q9LZA6
      UniProtKB/TrEMBL
      A0A178UB07, A0A5S9Y223
      Conserved Domains (2) summary
      cd07231
      Location:162 → 571
      Pat_SDP1-like; Sugar-Dependent 1 like lipase
      pfam11815
      Location:96 → 225
      DUF3336; Domain of unknown function (DUF3336)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZA6.1

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