U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    HAI1 PP2C protein (Clade A protein phosphatases type 2C) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836040, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    HAI1
    Official Full Name
    PP2C protein (Clade A protein phosphatases type 2C)
    Primary source
    TAIR:AT5G59220
    Locus tag
    AT5G59220
    See related
    Araport:AT5G59220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    highly ABA-induced PP2C gene 1; MNC17.13; MNC17_13; SAG113; senescence associated gene 113
    Summary
    Encodes a member of the PP2C family (Clade A protein phosphatases type 2C). Functions as a negative regulator of osmotic stress and ABA signaling.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HAI1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (23894404..23896939, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene myosin heavy chain-like protein Neighboring gene ncRNA Neighboring gene transcription factor-like protein Neighboring gene Ribosomal protein S8e family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Mutational analysis of Arabidopsis PP2CA2 involved in abscisic acid signal transduction. Guo XH, et al. Mol Biol Rep, 2010 Feb. PMID 19579056
    2. BPL3 binds the long non-coding RNA nalncFL7 to suppress FORKED-LIKE7 and modulate HAI1-mediated MPK3/6 dephosphorylation in plant immunity. Ai G, et al. Plant Cell, 2023 Jan 2. PMID 36269178, Free PMC Article
    3. The ABA-AtNAP-SAG113 PP2C module regulates leaf senescence by dephoshorylating SAG114 SnRK3.25 in Arabidopsis. Wang G, et al. Mol Hortic, 2023 Oct 30. PMID 37899482, Free PMC Article
    4. Selective inhibition of clade A phosphatases type 2C by PYR/PYL/RCAR abscisic acid receptors. Antoni R, et al. Plant Physiol, 2012 Feb. PMID 22198272, Free PMC Article
    5. An ABA-regulated and Golgi-localized protein phosphatase controls water loss during leaf senescence in Arabidopsis. Zhang K, et al. Plant J, 2012 Feb. PMID 22007837

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ABI1, ABI2, and HAI1 promoters of PP2C are regulated by repressors; BRM ATPase contributes to the repression of PP2C gene transcription
      Title: Chromatin remodeling for the transcription of type 2C protein phosphatase genes in response to salt stress.
    2. Mutational analysis of Arabidopsis PP2CA2 involved in abscisic acid signal transduction. [PP2CA2]
      Title: Mutational analysis of Arabidopsis PP2CA2 involved in abscisic acid signal transduction.
    3. SAG113, a negative regulator of ABA signal transduction, is specifically involved in the control of water loss during leaf senescence.
      Title: An ABA-regulated and Golgi-localized protein phosphatase controls water loss during leaf senescence in Arabidopsis.
    4. HAI1 is a negative regulator of osmotic adjustment during soil drying.
      Title: Unique drought resistance functions of the highly ABA-induced clade A protein phosphatase 2Cs.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001345339.1
    NM_125312.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cis-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    PP2C protein (Clade A protein phosphatases type 2C)
    NP_200730.1
    • highly ABA-induced PP2C gene 1 (HAI1); FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: response to water deprivation, response to abscisic acid stimulus; LOCATED IN: chloroplast; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: highly ABA-induced PP2C gene 2 (TAIR:AT1G07430.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23894404..23896939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125312.3 → NP_200730.1  PP2C protein (Clade A protein phosphatases type 2C) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200730.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q944I7, Q9FIF5
      UniProtKB/TrEMBL
      A0A5S9YFY1, A0A654GCF5
      Conserved Domains (1) summary
      smart00332
      Location:112 → 347
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain

    2. NM_001345339.1 → NP_001332613.1  PP2C protein (Clade A protein phosphatases type 2C) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UQ45, A0A1P8BHI8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FIF5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools