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    TOZ Transducin family protein / WD-40 repeat family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831538, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOZ
    Official Full Name
    Transducin family protein / WD-40 repeat family protein
    Primary source
    TAIR:AT5G16750
    Locus tag
    AT5G16750
    See related
    Araport:AT5G16750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5E19.90; F5E19_90; TORMOZEMBRYO DEFECTIVE
    Summary
    Encodes a nucleolar localized WD-40 repeat protein that is preferentially expressed in dividing cells and is required for regulated division planes and embryo development.
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    Genomic context

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    See TOZ in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Sequence:
    Chromosome: 5; NC_003076.8 (5504242..5509361, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene weak chloroplast movement under blue light protein (DUF827) Neighboring gene Transmembrane amino acid transporter family protein Neighboring gene Inositol 1,3,4-trisphosphate 5/6-kinase family protein Neighboring gene myb domain protein 9 Neighboring gene SART-1 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The TORMOZ gene encodes a nucleolar protein required for regulated division planes and embryo development in Arabidopsis. Griffith ME, et al. Plant Cell, 2007 Jul. PMID 17616738, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mutation of the TORMOZ (TOZ) gene yields embryos with aberrant cell division planes and arrested embryos that appear not to have established normal patterning.
      Title: The TORMOZ gene encodes a nucleolar protein required for regulated division planes and embryo development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_121681.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of small-subunit processome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transducin family protein / WD-40 repeat family protein
    NP_568338.2
    • TORMOZEMBRYO DEFECTIVE (TOZ); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Small-subunit processome, Utp13 (InterPro:IPR013934), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G49660.1); Has 153281 Blast hits to 38108 proteins in 953 species: Archae - 96; Bacteria - 13855; Metazoa - 64321; Fungi - 32637; Plants - 21715; Viruses - 0; Other Eukaryotes - 20657 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5504242..5509361 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121681.4 → NP_568338.2  Transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568338.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42339, Q8L830, Q93ZT0, Q9LFE2
      UniProtKB/TrEMBL
      A0A178UEE8, A0A5S9Y4R6
      Conserved Domains (4) summary
      COG2319
      Location:42 → 618
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:350 → 652
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08625
      Location:675 → 808
      Utp13; Utp13 specific WD40 associated domain
      sd00039
      Location:64 → 100
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFE2.1

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