U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PS2 Presenilin-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817540, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PS2
    Official Full Name
    Presenilin-2
    Primary source
    TAIR:AT2G29900
    Locus tag
    AT2G29900
    See related
    Araport:AT2G29900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6K5.3; F6K5_3; Presenilin-2
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PS2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (12749743..12751146)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Myb/SANT-like DNA-binding domain protein Neighboring gene villin-like 1 Neighboring gene F-box/RNI-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana. Smolarkiewicz M, et al. J Exp Bot, 2014 Jul. PMID 24723404, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_128544.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi-associated vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Presenilin-2
    NP_180551.1
    • Presenilin-2 (PS2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: intracellular signaling pathway; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22A, presenilin (InterPro:IPR001108); BEST Arabidopsis thaliana protein match is: Presenilin-1 (TAIR:AT1G08700.1); Has 475 Blast hits to 452 proteins in 108 species: Archae - 2; Bacteria - 0; Metazoa - 334; Fungi - 0; Plants - 63; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12749743..12751146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128544.4 → NP_180551.1  Presenilin-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180551.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0IGK6, Q9SIK7
      UniProtKB/TrEMBL
      A0A178VTM4, Q0WT05
      Conserved Domains (1) summary
      pfam01080
      Location:15 → 387
      Presenilin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SIK7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools