SUT4 sucrose transporter 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: SUT4
Official Full Name: sucrose transporter 4
Primary source: TAIR:AT1G09960
Locus tag: AT1G09960
See related: Araport:AT1G09960
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATSUC4; ATSUT4; F21M12.35; F21M12_35; SUC4; sucrose transporter 4; SUCROSE TRANSPORTER 4
Summary: low affinity (10mM) sucrose transporter in sieve elements (phloem)
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Genomic context

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See SUT4 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 6

Sequence:: Chromosome: 1; NC_003070.9 (3243986..3247216)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtSUC2 and AtSUC4 are important regulators in plant abiotic stress tolerance that use an abscisic acid (ABA) signaling pathway, which may be crossed with sucrose signaling.
Title: Arabidopsis AtSUC2 and AtSUC4, encoding sucrose transporters, are required for abiotic stress tolerance in an ABA-dependent pathway.
The increase in SUT4 expression may be the cause of an increase in SUT4-dependent apoplastic phloem loading in Arabidopsis.
Title: Photoassimilation, assimilate translocation and plasmodesmal biogenesis in the source leaves of Arabidopsis thaliana grown under an increased atmospheric CO2 concentration.
AtSUC4 is a sucrose/H(+) symporter directly in the tonoplast membrane.
Title: Vacuoles release sucrose via tonoplast-localised SUC4-type transporters.
AtSUC4 most likely catalyses proton-coupled sucrose export from the vacuole within the Arabidopsis cell. However, TMT1/2 probably represents a proton-coupled antiporter capable of high-capacity loading of glucose and sucrose into the vacuole.
Title: Proton-driven sucrose symport and antiport are provided by the vacuolar transporters SUC4 and TMT1/2.
SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose.
Title: Arabidopsis sucrose transporter SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose.
INT1 is correctly localized to the tonoplast, while sorting of the vacuolar sucrose transporter SUC4 is blocked in cis-Golgi stacks.
Title: Routes to the tonoplast: the sorting of tonoplast transporters in Arabidopsis mesophyll protoplasts.
AtSUC4 plays a significant role in the early phase of syncytium differentiation when functional plasmodesmata to the phloem are not yet established.
Title: Sucrose supply to nematode-induced syncytia depends on the apoplasmic and symplasmic pathways.
AtSUT4 is involved in transport and vacuolar storage of photosynthetically derived Sucrose.
Title: Identification of a vacuolar sucrose transporter in barley and Arabidopsis mesophyll cells by a tonoplast proteomic approach.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_100870.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables sucrose transmembrane transporter activity	IGI Inferred from Genetic Interaction more info	PubMed
enables sucrose transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables sucrose:proton symporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in sucrose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sucrose transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cis-Golgi network	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info
located_in vacuole	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: sucrose transporter 4

NP_172467.1

sucrose transporter 4 (SUT4); FUNCTIONS IN: sucrose transmembrane transporter activity, carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity, sucrose:hydrogen symporter activity; INVOLVED IN: sucrose transport, transmembrane transport; LOCATED IN: plasma membrane, vacuole, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sucrose/H+ symporter, plant (InterPro:IPR005989), Major facilitator superfamily MFS-1 (InterPro:IPR011701), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: sucrose-proton symporter 2 (TAIR:AT1G22710.1); Has 2568 Blast hits to 2441 proteins in 632 species: Archae - 30; Bacteria - 1104; Metazoa - 451; Fungi - 193; Plants - 403; Viruses - 0; Other Eukaryotes - 387 (source: NCBI BLink).