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    SK1 shikimate kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816730, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SK1
    Official Full Name
    shikimate kinase 1
    Primary source
    TAIR:AT2G21940
    Locus tag
    AT2G21940
    See related
    Araport:AT2G21940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSK1; F7D8.26; F7D8_26; shikimate kinase 1
    Summary
    Encodes a shikimate kinase. Its transcripts appear to be expressed most highly in mature embryos and senescing leaves, and its transcript levels rise during heat stress and recovery. It is believed to be localized to the chloroplast.
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    Genomic context

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    See SK1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (9350543..9353231)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene ncRNA Neighboring gene SKP1 interacting partner 6 Neighboring gene uncharacterized protein Neighboring gene stress enhanced protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and biochemical investigation of two Arabidopsis shikimate kinases: the heat-inducible isoform is thermostable. Fucile G, et al. Protein Sci, 2011 Jul. PMID 21520319, Free PMC Article
    2. Evolutionary diversification of plant shikimate kinase gene duplicates. Fucile G, et al. PLoS Genet, 2008 Dec. PMID 19057671, Free PMC Article
    3. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The heat-induced isoform, ATSK1, forms a homodimer in solution, the formation of which facilitates its relative thermostability compared to ATSK2.
      Title: Structural and biochemical investigation of two Arabidopsis shikimate kinases: the heat-inducible isoform is thermostable.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084467.2
    NM_001084468.1
    NM_001084469.1
    NM_001335780.1
    NM_001335781.1
    NM_127763.4
    NM_201778.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables shikimate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables shikimate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chorismate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within shikimate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    shikimate kinase 1
    NP_001077936.1
    • shikimate kinase 1 (SK1); FUNCTIONS IN: shikimate kinase activity, ATP binding; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Shikimate kinase (InterPro:IPR000623); BEST Arabidopsis thaliana protein match is: shikimate kinase 2 (TAIR:AT4G39540.2); Has 7808 Blast hits to 7808 proteins in 2397 species: Archae - 26; Bacteria - 5452; Metazoa - 44; Fungi - 128; Plants - 162; Viruses - 0; Other Eukaryotes - 1996 (source: NCBI BLink).
    NP_001077937.1
    • shikimate kinase 1 (SK1); FUNCTIONS IN: shikimate kinase activity, ATP binding; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Shikimate kinase (InterPro:IPR000623); BEST Arabidopsis thaliana protein match is: shikimate kinase 2 (TAIR:AT4G39540.2); Has 7757 Blast hits to 7757 proteins in 2385 species: Archae - 26; Bacteria - 5408; Metazoa - 44; Fungi - 134; Plants - 162; Viruses - 0; Other Eukaryotes - 1983 (source: NCBI BLink).
    NP_001077938.1
    • shikimate kinase 1 (SK1); FUNCTIONS IN: shikimate kinase activity, ATP binding; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Shikimate kinase (InterPro:IPR000623); BEST Arabidopsis thaliana protein match is: shikimate kinase 2 (TAIR:AT4G39540.2); Has 7831 Blast hits to 7831 proteins in 2412 species: Archae - 26; Bacteria - 5482; Metazoa - 44; Fungi - 134; Plants - 162; Viruses - 0; Other Eukaryotes - 1983 (source: NCBI BLink).
    NP_179785.2
    • shikimate kinase 1 (SK1); FUNCTIONS IN: shikimate kinase activity, ATP binding; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Shikimate kinase (InterPro:IPR000623); BEST Arabidopsis thaliana protein match is: shikimate kinase 2 (TAIR:AT4G39540.2); Has 7831 Blast hits to 7831 proteins in 2412 species: Archae - 26; Bacteria - 5482; Metazoa - 44; Fungi - 134; Plants - 162; Viruses - 0; Other Eukaryotes - 1983 (source: NCBI BLink).
    NP_973507.2
    • shikimate kinase 1 (SK1); FUNCTIONS IN: shikimate kinase activity, ATP binding; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Shikimate kinase (InterPro:IPR000623); BEST Arabidopsis thaliana protein match is: shikimate kinase 2 (TAIR:AT4G39540.2); Has 7831 Blast hits to 7831 proteins in 2412 species: Archae - 26; Bacteria - 5482; Metazoa - 44; Fungi - 134; Plants - 162; Viruses - 0; Other Eukaryotes - 1983 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9350543..9353231
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127763.4 → NP_179785.2  shikimate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179785.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3DN83, Q3EBW8, Q8GT76, Q9SJ05
      UniProtKB/TrEMBL
      A0A178VV30, A0A5S9X0D4, A0A654EV23
      Conserved Domains (1) summary
      PLN02199
      Location:1 → 303
      PLN02199; shikimate kinase

    2. NM_001335780.1 → NP_001323559.1  shikimate kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VWR1, A8MRG1
      Conserved Domains (2) summary
      PLN02199
      Location:1 → 256
      PLN02199; shikimate kinase
      cd00464
      Location:104 → 256
      SK; Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis ...

    3. NM_201778.3 → NP_973507.2  shikimate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973507.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3DN83, Q3EBW8, Q8GT76, Q9SJ05
      UniProtKB/TrEMBL
      A0A178VV30, A0A5S9X0D4, A0A654EV23
      Conserved Domains (1) summary
      PLN02199
      Location:1 → 303
      PLN02199; shikimate kinase

    4. NM_001084467.2 → NP_001077936.1  shikimate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077936.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VWR1, A8MRG1
      Conserved Domains (2) summary
      PLN02199
      Location:1 → 256
      PLN02199; shikimate kinase
      cd00464
      Location:104 → 256
      SK; Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis ...

    5. NM_001084468.1 → NP_001077937.1  shikimate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077937.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VV30, F4IIJ2
      Conserved Domains (2) summary
      PLN02199
      Location:1 → 304
      PLN02199; shikimate kinase
      cd00464
      Location:105 → 262
      SK; Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis ...

    6. NM_001335781.1 → NP_001323558.1  shikimate kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VWR1, A8MRG1
      Conserved Domains (2) summary
      PLN02199
      Location:1 → 256
      PLN02199; shikimate kinase
      cd00464
      Location:104 → 256
      SK; Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis ...

    7. NM_001084469.1 → NP_001077938.1  shikimate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077938.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3DN83, Q3EBW8, Q8GT76, Q9SJ05
      UniProtKB/TrEMBL
      A0A178VV30, A0A5S9X0D4, A0A654EV23
      Conserved Domains (1) summary
      PLN02199
      Location:1 → 303
      PLN02199; shikimate kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJ05.2

    Gene LinkOut

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