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    TI2 trypsin inhibitor protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818953, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TI2
    Official Full Name
    trypsin inhibitor protein 2
    Primary source
    TAIR:AT2G43520
    Locus tag
    AT2G43520
    See related
    Araport:AT2G43520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTI2; T1O24.26; trypsin inhibitor protein 2
    Summary
    Encodes putative trypsin inhibitor protein which may function in defense against herbivory. Member of the defensin-like (DEFL) family.
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    Genomic context

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    See TI2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (18068425..18069416)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Plant regulator RWP-RK family protein Neighboring gene trypsin inhibitor protein 1 Neighboring gene scorpion toxin-like knottin superfamily protein Neighboring gene Scorpion toxin-like knottin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Population genetics of tandem trypsin inhibitor genes in Arabidopsis species with contrasting ecology and life history. Clauss MJ, et al. Mol Ecol, 2003 May. PMID 12694291
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_129913.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables sodium channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    trypsin inhibitor protein 2
    NP_181880.1
    • trypsin inhibitor protein 2 (TI2); FUNCTIONS IN: serine-type endopeptidase inhibitor activity; INVOLVED IN: defense response; LOCATED IN: endomembrane system, extracellular region; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Scorpion long chain toxin (InterPro:IPR002061), Knottin (InterPro:IPR003614); BEST Arabidopsis thaliana protein match is: Scorpion toxin-like knottin superfamily protein (TAIR:AT1G47540.1); Has 146 Blast hits to 146 proteins in 7 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 145; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18068425..18069416
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129913.3 → NP_181880.1  trypsin inhibitor protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181880.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22866, Q67YC6, Q6ZZT9
      UniProtKB/TrEMBL
      A0A178W058, A0A5S9X6N6
      Conserved Domains (1) summary
      pfam00537
      Location:28 → 90
      Toxin_3; Scorpion toxin-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22866.1

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