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    ACA2 alpha carbonic anhydrase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817367, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ACA2
    Official Full Name
    alpha carbonic anhydrase 2
    Primary source
    TAIR:AT2G28210
    Locus tag
    AT2G28210
    See related
    Araport:AT2G28210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alpha carbonic anhydrase 2; ATACA2; T3B23.12; T3B23_12
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    Genomic context

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    See ACA2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (12029666..12033096)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene C2H2-type zinc finger family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene aspartic proteinase CDR1-like protein Neighboring gene aspartic proteinase CDR1-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Participation of Two Carbonic Anhydrases of the Alpha Family in Photosynthetic Reactions in Arabidopsis thaliana. Zhurikova EM, et al. Biochemistry (Mosc), 2016 Oct. PMID 27908242
    2. Calmodulin activation of an endoplasmic reticulum-located calcium pump involves an interaction with the N-terminal autoinhibitory domain. Hwang I, et al. Plant Physiol, 2000 Jan. PMID 10631259, Free PMC Article
    3. Characterization and expression analysis of genes encoding alpha and beta carbonic anhydrases in Arabidopsis. Fabre N, et al. Plant Cell Environ, 2007 May. PMID 17407539
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to carbon dioxide IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha carbonic anhydrase 2
    NP_001318303.1
    • alpha carbonic anhydrase 2 (ACA2); FUNCTIONS IN: carbonate dehydratase activity, zinc ion binding; INVOLVED IN: response to carbon dioxide, one-carbon metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: stem, root; CONTAINS InterPro DOMAIN/s: Carbonic anhydrase, alpha-class, catalytic domain (InterPro:IPR001148), Carbonic anhydrase, alpha-class, conserved site (InterPro:IPR018338), Carbonic anhydrase, CAH1-like (InterPro:IPR018340); BEST Arabidopsis thaliana protein match is: alpha carbonic anhydrase 7 (TAIR:AT1G08080.1); Has 3295 Blast hits to 3278 proteins in 530 species: Archae - 0; Bacteria - 691; Metazoa - 2036; Fungi - 83; Plants - 323; Viruses - 2; Other Eukaryotes - 160 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12029666..12033096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336148.1 → NP_001318303.1  alpha carbonic anhydrase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VW72, A0A5S9X232, A0A7G2EFR1
      Conserved Domains (1) summary
      cd03124
      Location:48 → 270
      alpha_CA_prokaryotic_like; Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

    2. NM_001336149.1 → NP_001323618.1  alpha carbonic anhydrase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AXK4
    Nucleotide Protein
    Heading Accession and Version

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