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    CG4622 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37919, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4622provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035021
    Locus tag
    Dmel_CG4622
    See related
    AllianceGenome:FB:FBgn0035021
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4622; dZcchc8; Itp; ZCCHC8; ZCHC8
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Predicted to be part of catalytic step 2 spliceosome. Is expressed in organism. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4622 in Genome Data Viewer
    Location:
    60D4-60D5; 2-107 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24533374..24556300, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20420897..20443823, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene BRCA2, DNA repair associated Neighboring gene Ionotropic receptor 60e Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ion transport peptide Neighboring gene Nucleosome remodeling factor - 38kD Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of codon usage on gene expression are promoter context dependent. Yang Q, et al. Nucleic Acids Res, 2021 Jan 25. PMID 33410890, Free PMC Article
    2. Gene-specific cell labeling using MiMIC transposons. Gnerer JP, et al. Nucleic Acids Res, 2015 Apr 30. PMID 25712101, Free PMC Article
    3. A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Molleston JM, et al. Genes Dev, 2016 Jul 15. PMID 27474443, Free PMC Article
    4. A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses. Baranski TJ, et al. PLoS Genet, 2018 Apr. PMID 29608557, Free PMC Article
    5. Copper homeostasis gene discovery in Drosophila melanogaster. Norgate M, et al. Biometals, 2007 Jun. PMID 17216353

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4622-PA
    CG4622-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24533374..24556300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038882.3 → NP_001033971.2  uncharacterized protein Dmel_CG4622, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033971.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2PE14, Q5BHV6, Q9W153
      Conserved Domains (1) summary
      smart00581
      Location:229 → 281
      PSP; proline-rich domain in spliceosome associated proteins

    2. NM_138085.4 → NP_611929.1  uncharacterized protein Dmel_CG4622, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611929.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2PE14, Q5BHV6, Q9W153
      Related
      FBpp0072251
      Conserved Domains (1) summary
      smart00581
      Location:229 → 281
      PSP; proline-rich domain in spliceosome associated proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2PE14.2 Q2PE14

    Gene LinkOut

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